J Behav Addict. 2016 Jul 21: 1-4.
I-Gola M1,2, Potenza MN3,4,5.
abstract
Background
Okungcono kakhulu ukukuqonda ukusetshenziswa kwezinkinga zocansi okuyinkinga (i-PPU) nokungenelela kuhlale kuphakama mpikiswano kakhulu, nge-obsessive-activive disorder (OCD) nezinhlaka zokulutha. Siphenye ukusebenza kwe-serotonin-reuptake inhibitor paroxetine kuhlanganiswa nokwelashwa okuphathelene nokuqonda ekwelapheni ukusetshenziswa kwezinkinga zocansi okuyinkinga (PPU).
Isethulo secala
Abesilisa abathathu abathandana nabesilisa abane-PPU baphathwa ngokwelashwa okuphathelene nokuqonda kanye ne-paroxetine. Imvamisa yokusetshenziswa kwezithombe zobulili ezingcolile, ezinye izindlela zokuziphatha zocansi, nokukhathazeka zahlolwa ngesikhathi sokwelashwa.
Ingxoxo
Ukwelashwa kwe-paroxetine, yize kubonakala sengathi kusebenza kahle ekuqaleni ekunciphiseni ukusetshenziswa kwezithombe zobulili ezingcolile nokukhathazeka, kwavela kuhlobene nokuziphatha okusha okuphoqelelayo kokuziphatha kocansi ngemuva kwezinyanga ze-3.
iziphetho
I-Paroxetine ingabamba isethembiso sokunciphisa okwesikhashana kwe-PPU nokukhathazeka okuhlobene nayo, kodwa izindlela zokuziphatha zocansi ezintsha ezingaba nomphumela zingavela. Amacala asikisela ukuthi i-PPU ingavela ezizindeni eziningi. Siphakamisa incazelo yemiphumela ngokususelwa ocwaningweni lwakamuva lwe-neurosciology mayelana nokuziphatha kobulili nokusebenzisa kabi utshwala.
KEYWORDS:
uchungechunge lwamacala i-paroxetine; ekhemisi; ukusetshenziswa kwezinkinga zocansi okuyinkinga
I-PMID:27440474
I-DOI:10.1556/2006.5.2016.046
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