Age 21 – 1 year: I don’t like to overreact but the benefits have made me a completely different person

A little background: I’m 21. The last time I watched P was January 15th, of 2016. WOW. Feels amazing to type that out. Especially because nobody else really knows except for me and the people of nofap. When I discovered this sub I meant to go ahead with it as a new years resolution but […]

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Opioid-Dependent Anticipatory Negative Contrast and Binge-Like Eating in Rats with Limited Access to Highly Preferred Food (2007)

Neuropsychopharmacology (2008) 33, 524–535; doi:10.1038/sj.npp.1301430; published online 18 April 2007 Pietro Cottone1,2,3,4, Valentina Sabino1,2,4, Luca Steardo3 and Eric P Zorrilla1,2 1Committee on the Neurobiology of Addictive Disorders, The Scripps Research Institute, La Jolla, CA, USA 2Harold L. Dorris Neurological Research Institute, The Scripps Research Institute, La Jolla, CA, USA 3Department of Human Physiology and Pharmacology, University of Rome La […]

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Bingeing rats: A model of intermittent excessive behavior? (2006)

Appetite. Author manuscript; available in PMC 2007 Jan 15. Published in final edited form as: Appetite. 2006 Jan; 46(1): 11–15. Published online 2005 Sep 26. doi:  10.1016/j.appet.2004.09.002 PMCID: PMC1769467 NIHMSID: NIHMS15066 Rebecca L. Corwin Abstract Intermittent excessive behaviors (IEB) characterize a variety human disorders including binge eating, drug abuse, alcoholism, aberrant sexual conduct, and compulsive […]

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Prolonged High Fat Diet Reduces Dopamine Reuptake without Altering DAT Gene Expression (2013)

Jackson J. Cone, Elena H. Chartoff, David N. Potter, Stephanie R. Ebner, Mitchell F. Roitman Abstract The development of diet-induced obesity (DIO) can potently alter multiple aspects of dopamine signaling, including dopamine transporter (DAT) expression and dopamine reuptake. However, the time-course of diet-induced changes in DAT expression and function and whether such changes are dependent […]

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Reversal of dopamine system dysfunction in response to high fat diet (2013)

Obesity (Silver Spring). Author manuscript; available in PMC 2014 Jun 1. Published in final edited form as: Obesity (Silver Spring). 2013 Dec; 21(12): 2513–2521. Published online 2013 May 29. doi:  10.1002/oby.20374 PMCID: PMC3700634 NIHMSID: NIHMS435903 JesseLea Carlin,1 Tiffany E. Hill-Smith,2 Irwin Lucki,1,2 and Teresa M. Reyes1 Abstract Objective To test whether high fat diet (HFD) […]

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Rats that binge eat fat-rich food do not show somatic signs or anxiety associated with opiate-like withdrawal: implications for nutrient-specific food addiction behaviors (2011)

Physiol Behav. Author manuscript; available in PMC 2012 Oct 24. Published in final edited form as: Physiol Behav. 2011 Oct 24; 104(5): 865–872. Published online 2011 May 24. doi:  10.1016/j.physbeh.2011.05.018 PMCID: PMC3480195 NIHMSID: NIHMS299784 Miriam E. Bocarsly,1 Laura A. Berner,1 Bartley G. Hoebel,1 and Nicole M. Avena1,2 Abstract Previous studies suggest that binge eating sugar […]

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Differential expression of CART in feeding and reward circuits in binge eating rat model (2015)

Behav Brain Res. 2015 Sep 15;291:219-31. doi: 10.1016/j.bbr.2015.05.030. Bharne AP1, Borkar CD1, Subhedar NK2, Kokare DM3. Highlights CART expression increases during binge as compare to that in sated condition. Higher dose of CART or rimonabant requires to reduce food intake in binging rat. Binge habit induces neuroplasticity in lateral hypothalamus and hippocampus. Disparate CART pathways […]

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