Published in final edited form as: J Neurosci. 2008 Jul 16; 28(29): 7344–7349. doi: 10.1523/JNEUROSCI.1043-08.2008 PMCID: PMC2610249 NIHMSID: NIHMS66599 William Renthal,1 Tiffany L. Carle,1 Ian Maze,1 Herbert E. Covington, III,1 Hoang-Trang Truong,1 Imran Alibhai,1 Arvind Kumar,1 Rusty L. Montgomery,2 Eric N. Olson,2 and Eric J. Nestler1,* Go to: Abstract The molecular mechanisms underlying the transition […]
Read More… from DeltaFosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure (2008)
This is going to long. I warned you. And it’s also going to be uncomfortable, even painful and scary. Hope is scary. And one of the main reasons people struggle with addiction is because they are scared of what’s inside themselves. I would also add that I have written this in one go, in five hours. […]
Read More… from Age 19 – Addiction is no longer a part of my life
After one year and one month of nofap, no porn or sexual thoughts I’m a different person from inside out. I have completely changed. My voice is stronger and more masculine. My brain is sharper. My social anxiety is non-existent. I did not relapse even once i think nofap itself gave me the power. My […]
Read More… from Age 19 – Mind blowing will power, better self control, confidence, deeper voice
I was eleven years old when I first came across a pornographic image. It was a video case that me and my younger brother had found in the back of the trunk of our silver Ford Aerostar. Even after all these years I can clearly recall the image of this pornographic material plain as day. […]
Read More… from Age 25 – Giving up the lure of porn
BEFORE: I have suffered so much in my life, for over 3 decades of dysfunctional relationships, a stressed/dead marriage with lousy sex (mostly cause of me) ED, porn addiction and sex addiction. Intermixed with all that is anxiety and often panic and lots of anger and blame. My path is littered with self-help books, different […]
Read More… from Age 52 – Porn-induced ED gone, addiction and fantasy almost nil – after 35 years
I am proud to say I have gone 50 days without shooting a load, not even a wet dream. I don’t even feel horny anymore (but I’m not flatlining) and I think I know why….. I have thrown myself into my music. I am already an OK pianist, but since January I have been pushing […]
Read More… from Age 34 – I’m now 100% confident in social situations, and find that I don’t care what people think of me
Hello fellows, This is my 2nd 90 day report. My longest streak was 127 days. My current streak is my second longest. My third longest was 58 days and then I had several 3 or 4 week streaks since I started with nofap maybe 2 years ago. Generally I can say that I like nofap […]
Read More… from 2nd 90 day report: The benefits seem to come in waves.
So yesterday I broke a nine week no-porn streak. I’m going through a bunch of shit right now, and I reasoned that watching porn would free up some willpower for other challenges. I can’t honestly say it was a bad decision to have made, but I’m looking forward to starting my next streak soon. BENEFITS: […]
Read More… from 9 weeks – Depression is hugely improved, Porn was sapping me of my willpower
I had almost forgotten the period of my life where I struggled with masturbation and porn. It was so long ago. But I did have a problem – and I beat it. So, I thought I would share the story and the wonderful things that came from giving up. Throw back two years – when […]
Read More… from Age 40s – Two years later…. No ED. Married with little baby
Khemiri, Lotfi et al. European Neuropsychopharmacology Lotfi Khemiri, Pia Steensland, Joar Guterstam, Olof Beck, Arvid Carlsson, Johan Franck, Nitya Jayaram-Lindström DOI: http://dx.doi.org/10.1016/j.euroneuro.2015.09.018 Article Outline 1. Introduction 2. Experimental Procedures 2.1. Participants 2.2. Study Design 2.3. Alcohol Craving Test Sessions 2.4. Clinical measures 2.5. Behavioral task of impulsivity 2.6. Statistical Analysis 3. Results 3.1. Participants 3.2. […]
Read More… from The Effects of the Monoamine Stabilizer (-)-OSU6162 on Craving in Alcohol Dependent Individuals: A Human Laboratory Study (2015)