Age 52 – Porn-induced ED gone, addiction and fantasy almost nil – after 35 years

BEFORE: I have suffered so much in my life, for over 3 decades of dysfunctional relationships, a stressed/dead marriage with lousy sex (mostly cause of me) ED, porn addiction and sex addiction. Intermixed with all that is anxiety and often panic and lots of anger and blame. My path is littered with self-help books, different […]

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Age 34 – I’m now 100% confident in social situations, and find that I don’t care what people think of me

I am proud to say I have gone 50 days without shooting a load, not even a wet dream. I don’t even feel horny anymore (but I’m not flatlining) and I think I know why….. I have thrown myself into my music. I am already an OK pianist, but since January I have been pushing […]

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The Effects of the Monoamine Stabilizer (-)-OSU6162 on Craving in Alcohol Dependent Individuals: A Human Laboratory Study (2015)

Khemiri, Lotfi et al. European Neuropsychopharmacology Lotfi Khemiri, Pia Steensland, Joar Guterstam, Olof Beck, Arvid Carlsson, Johan Franck, Nitya Jayaram-Lindström DOI: http://dx.doi.org/10.1016/j.euroneuro.2015.09.018 Article Outline 1. Introduction 2. Experimental Procedures 2.1. Participants 2.2. Study Design 2.3. Alcohol Craving Test Sessions 2.4. Clinical measures 2.5. Behavioral task of impulsivity 2.6. Statistical Analysis 3. Results 3.1. Participants 3.2. […]

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The monoamine stabilizer (−)-OSU6162 counteracts downregulated dopamine output in the nucleus accumbens of long-term drinking Wistar rats (2015)

Kristin Feltmann1,†, Ida Fredriksson1,†, Malin Wirf1, Björn Schilström2,3 and Pia Steensland1,* Article first published online: 14 OCT 2015 DOI: 10.1111/adb.12304 Abstract We recently established that the monoamine stabilizer (−)-OSU6162 (OSU6162) decreased voluntary alcohol-mediated behaviors, including alcohol intake and cue/priming-induced reinstatement, in long-term drinking rats, while blunting alcohol-induced dopamine output in the nucleus accumbens (NAc) of alcohol-naïve […]

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Neural Pathways of Stress Integration: Relevance to Alcohol Abuse, James P. Herman, Ph.D.

LINK  James P. Herman, Ph.D., is a professor in the Departments of Psychiatry and Behavioral Neuroscience, University of Cincinnati, Cincinnati, Ohio. Stress is a critical component in the development, maintenance, and reinstatement of addictive behaviors, including alcohol use. This article reviews the current state of the literature on the brain’s stress response, focusing on the […]

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The Darkness Within Individual Differences in Stress (2015), George F. Koob, Ph.D.

The Darkness Within Individual Differences in Stress Wednesday, April 01, 2015 By: George F. Koob, Ph.D. Editor’s Note: Numerous factors make us react to situations differently: age, gender, education, relationships, socioeconomic status, environment, cultural background, life experience. But as our author describes, biological bases, such as the way genetics and neurochemicals affect our brains, are […]

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