Throughout my teenage years, I did nothing but masturbate, internet binge, and play video games. Along with that, I had begun to develop crippling anxiety. At first it was just around girls, but then it evolved into being afraid of everything. I’m 19 now and I had a really bad experience with a girl 6 […]
Read More… from Age 19 – I just experienced what it feels like to love a girl
Biomed Res Int. 2014; 2014: 109786. Published online 2014 Jun 12. doi: 10.1155/2014/109786 PMCID: PMC4075088 Mauro Pettorruso, 1 ,* Luisa De Risio, 1 Giovanni Martinotti, 2 Marco Di Nicola, 1 Filippo Ruggeri, 1 Gianluigi Conte, 1 Massimo Di Giannantonio, 2 and Luigi Janiri 1 Author information ► Article notes ► Copyright and License information ► […]
Read More… from Targeting the Glutamatergic System to Treat Pathological Gambling: Current Evidence and Future Perspectives (2014)
Indian J Psychiatry. 2015 Jan-Mar;57(1):100-1. doi: 10.4103/0019-5545.148540. Poddar S1, Sayeed N1, Mitra S2. Sir, Though Diagnostic and Statistical Manual of Mental Disorders, Fifth edition (DSM-5) does not recognize this as an official category, internet game addiction (IGD) is becoming a serious problem in countries which have wide access to the internet.[1,2] DSM-5 presently proposes and […]
Read More… from Internet gaming disorder: Application of motivational enhancement therapy principles in treatment (2015)
Cereb Cortex. 2014 Apr; 24(4): 845–858. Published online 2012 Nov 25. doi: 10.1093/cercor/bhs362 Niels Hansen and Denise Manahan-Vaughan This article has been cited by other articles in PMC. Go to: Abstract Dopamine (DA) plays an essential role in the enablement of cognition. It adds color to experience-dependent information storage, conferring salience to the memories that […]
Read More… from Dopamine D1 D5 Receptors Mediate Informational Saliency that Promotes Persistent Hippocampal Long Term Plasticity (2014)
J Neurosci. 2008 Dec 10;28(50):13390-400. doi: 10.1523/JNEUROSCI.2680-08.2008. Tran AH1, Uwano T, Kimura T, Hori E, Katsuki M, Nishijo H, Ono T. Abstract The human hippocampus is critical for learning and memory. In rodents, hippocampal pyramidal neurons fire in a location-specific manner, forming relational representations of environmental cues. The importance of glutamatergic systems in learning and […]
Read More… from Dopamine D1 receptor modulates hippocampal representation plasticity to spatial novelty (2008)
The Journal of Neuroscience, 20 May 2015, 35(20): 7964-7976; doi: 10.1523/JNEUROSCI.3884-14.2015 Xue Sun1,3, Nils B. Kroemer3,4,5, Maria G. Veldhuizen3,4, Amanda E. Babbs3, Ivan E. de Araujo3,4, Darren R. Gitelman3,6,7,8, Robert S. Sherwin9, Rajita Sinha4, and Dana M. Small1,2,3,4,10 Abstract In rodents, food-predictive cues elicit eating in the absence of hunger (Weingarten, 1983). This behavior is […]
Read More… from Basolateral Amygdala Response to Food Cues in the Absence of Hunger Is Associated with Weight Gain Susceptibility (2015)
Int J Neuropsychopharmacol. 2015 Apr 9. pii: pyv041. doi: 10.1093/ijnp/pyv041. Norbury A1, Kurth-Nelson Z2, Winston JS2, Roiser JP2, Husain M2. Abstract Background: Sensation-seeking is a trait that constitutes an important vulnerability factor for a variety of psychopathologies with high social cost. However, little is understood either about the mechanisms underlying motivation for intense sensory experiences […]
Read More… from Dopamine Regulates Approach-Avoidance in Human Sensation-Seeking (2015)
PLoS One. 2015 May 11;10(5):e0126710. doi: 10.1371/journal.pone.0126710. eCollection 2015. Ohnishi YH1, Ohnishi YN2, Nakamura T3, Ohno M4, Kennedy PJ5, Yasuyuki O6, Nishi A7, Neve R8, Tsuzuki T4, Nestler EJ5. Abstract ΔFosB is a stable transcription factor which accumulates in the nucleus accumbens (NAc), a key part of the brain’s reward circuitry, in response to chronic […]
Read More… from PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens (2015)
At the meeting of the Society for Neuroscience in Washington, DC, there are 30,000 delegates. And one of them has changed the way the others look at desire. Amy Fleming meets Dr Kent Berridge From INTELLIGENT LIFE magazine, May/Jue 2015 THE STATELY STRETCH of New York Avenue, in Washington, DC, that runs between the White […]
Read More… from (L) The Science of Craving: Kent Berridge (2015)
I’ve been PMO free for more than 90 days. I don’t post a lot on nofap.com but I feel the need to share what has helped me along the way as I know you’re all struggling right along with me…fighting the good fight. I’m not looking for encouragement or congratulations. I just want to share […]
Read More… from 90 days – Married: Sharing what has FINALLY gotten me to this point in my life