Cereb Cortex. 2009 Feb;19(2):435-44. doi: 10.1093/cercor/bhn094. Winstanley CA, Bachtell RK, Theobald DE, Laali S, Green TA, Kumar A, Chakravarty S, Self DW, Nestler EJ. Abstract Increased impulsivity caused by addictive drugs is believed to contribute to the maintenance of addiction and has been linked to hypofunction within the orbitofrontal cortex (OFC). Recent data indicate that […]
Read More… from Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex (2009)
Dialogues Clin Neurosci. 2013 Dec;15(4):431-43. Eric J. Nestler, MD, PhD* Author information ► Copyright and License information ► Go to: Abstract Despite the importance of numerous psychosocial factors, at its core, drug addiction involves a biological process: the ability of repeated exposure to a drug of abuse to induce changes in a vulnerable brain that […]
Read More… from Cellular basis of memory for addiction (2013)
I’ve been dealing with anxiety issues over the past few years, or rather trying to find a reason for it. Not just anxiety but the awkwardness that I really couldn’t understand. Why could I speak with some people just fine, but most people was a complete struggle? I knew I could do it, but whatever […]
Read More… from I was anxious 24/7, irritable, awkward, and had poor concentration
Who I am: A 28 year old regular guy. Started PMO when I was about 18. Feel free to read my story. I realize that this is a long post and I’m mostly posting this for personal reasons, to finally get it off my chest. Maybe someone out there can relate. Before: On average I […]
Read More… from Age 28 – HOCD almost gone, no longer depressed or anxious, in a great relationship
The process of NoFap has been a lifechanging experience. Notice I wrote it as a process, continually ongoing, everyday as a different and unique challenge. As a fapstronaut with 13 years under his belt, one day the concept of turning on my computer, opening my stash and f’ing myself, literally and figuratively made me question […]
Read More… from 110 days – the ultimate form of self-mastery/self-actualization
Last Halloween I attended a dance and the girls were in their outfits. I was with a friend of mine. As we stood awkwardly on the edge of the dance floor watching ladies dance, I leaned to my friend and asked, “What if a girl walked over and offered to blow you behind the speaker?” […]
Read More… from Age 35 – 90 days: my drug counselor said “You’re addicted to internet porn aren’t you.”
I thought when I reached 90 days of NoFap, I would have seen all the benefits of my experiment. At the six-month mark, life is only getting better. To be fair, early on, I started a meditation practice to teach my brain to control the urges. Every day now, I sit for at least ten […]
Read More… from Female – Age 31: At the 6 month mark, life is only getting better
Front. Integr. Neurosci., 20 July 2012 | doi: 10.3389/fnint.2012.00049 Jeff A. Beeler1*, Cristianne R. M. Frazier2 and Xiaoxi Zhuang1,2 1Department of Neurobiology, The University of Chicago, Chicago, IL, USA 2Committee on Neurobiology, The University of Chicago, Chicago, IL, USA Accumulating evidence indicates integration of dopamine function with metabolic signals, highlighting a potential role for dopamine […]
Read More… from Putting desire on a budget: dopamine and energy expenditure, reconciling reward and resources (2012)
I hit the 90 day mark and I wanted to report on some the benefits I’ve seen in my life: I feel better about myself. I haven’t had a marked increase in confidence as I was already a fairly confident guy to begin with, but what I’ve noticed instead is that I just feel really, […]
Read More… from Age 28 – Married: incredible life improvements
Know what? I feel like a snake after it sheds its skin. Though it is far from over…the urges for porn are on a very low controllable level, but rewiring to the real thing just started. Right now, I just sense the seeds growing that I planted last year in july when I read an […]
Read More… from Age 24 – (ED) 90 days: Escape From the “Comfort-Zone Prison”