Periadolescent Mice Show Enhanced ΔFosB Upregulation in Response to Cocaine and Amphetamine (2002)

J Neurosci. 2002 Nov 1;22(21):9155-9.   Ehrlich ME, Sommer J, Canas E, Unterwald EM. Source The Nathan Kline Institute, Orangeburg, New York, 10962, USA. [email protected] Abstract Children and adolescents are increasingly exposed to psychostimulants, either illicitly or for the treatment of common neuropsychiatric conditions, such as attention deficit disorder with and without hyperactivity. Despite the […]

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Neuroplasticity in addiction: cellular and transcriptional perspectives (2012)

Front Mol Neurosci. 2012; 5: 99. Published online 2012 November 12.. doi:  10.3389/fnmol.2012.00099 PMCID: PMC3495339 Heather B. Madsen,1,† Robyn M. Brown,1,*† and Andrew J. Lawrence1,2 Author information ► Article notes ► Copyright and License information ► Go to: Abstract Drug addiction is a chronic, relapsing brain disorder which consists of compulsive patterns of drug-seeking and […]

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(L) Study Shows Working Memory Is Driven By Prefrontal Cortex And Dopamine (2012)

December 18, 2012 redOrbit Staff & Wire Reports – Your Universe Online One of the unique features of the human mind is its ability re-prioritize its goals and priorities as situations change and new information arises. This happens when you cancel a planned cruise because you need the money to repair your broke-down car, or […]

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The two faces of depression – two studies switch off symptoms in mice, but in opposite ways

In a lab at Stanford University, a mouse is showing signs of depression. For around 10 weeks, it has experienced a series of irritations, from bouts without food or water, to erratic sleep patterns. Now, its motivation is low—when picked up by the tail, it makes few attempts to escape, and it doesn’t try to […]

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