Mefuta e phahameng ea dopamine e ka loantša maikutlo ka mefuta eohle ea litsela tse sa lebelloang.
Lithethefatsi tsa Parkinson 'li entse hore ke be papali ea chelete, lesholu le bosodoma'
Lekhotla la Fora le ikemiselitse ho fana ka tšenyo e kholo ho ntate oa bana ba babeli ea lilemo li 47 ea nang le lefu la Parkinson ea neng a ahloloa hore o fetotsoe papali ea chelete le lesholu, ka litakatso tse qobelloang tsa bosodoma, ke lithethefatsi tseo a neng a phekoloa ka tsona .
Didier Jambart, mosebeletsi oa Lefapha la Ts'ireletso, o ntse a qosa litšenyehelo tsa € 400,000 kamora ho fuoa lengolo la lithethefatsi tsa dopamine agonist nyeoeng e ntseng e ithutoa ka hloko ke babuelli ba molao ba emelang bakuli ba Parkinson Borithane, US le Canada. Joalo ka Jambart, ba bolela hore ba fuoe tlhaiso-leseling e fokolang ka litla-morao tse ferekanyang, tse hakantsoeng hore li ka ama liperesente tse 15 tsa ba sebelisang lithethefatsi.
'Ke ne nke ke ka pheta pale ena le likhoeling tse' maloa tse fetileng ntle le ho senyeha, 'ho boletse Jambart. 'Ke tseba ka mehlala e meng e tšabehang mona Fora, ho kenyelletsa le motho ea neng a koaletsoe chankaneng ka lebaka la ho qobelloa ho becha, le basali ba ileng ba qetella ba etsa botekatse malapeng ka lebaka la takatso ea bona ea thobalano.' O ile a ba le mekoloto ea papali ea chelete ea € 130,000 ha a ntse a utsoetsa ba lelapa la hae, metsoalle le baahisani ho tšehetsa chelete ea hae ea ho rata chelete. O bile a rekisa lintho tsa ho bapala tsa bara ba hae ba babeli ba banyenyane.
Li-agonists tsa Dopamine, tse etsisang methapo-kutlo ea lik'hemik'hale, li sebelisoa litlhare tse 'maloa tse tsebahalang tse atisang ho abeloa Parkinson's, lefu le fokolisang le amang batho ba ka bang 120,000 Borithane. Maemong a mangata, li sebetsana ka katleho le matšoao a kenyeletsang ho thothomela ha mesifa le ho lieha ho sisinyeha.
Empa pele selemo se qala ho noa meriana ea hae, Jambart o ile a utloa matšoao a pele a seo a se bitsang 'naha ea Jekyll le Hyde'. Nakong ea lipalo tse phahameng o ile a qala ho beha libete tsa mabelo a lipere marang-rang. Empa ka December 2004, o ile a etsa lekhetlo la pele ho a mararo a ho ipolaea. Selemong se hlahlamang o ile a qala ho ts'oasa marang-rang a marang-rang bakeng sa balekane bao a ba memileng hae.
'Hang ha re mo bona re ile ra tseba hang-hang hore ke li-agonists tsa dopamine,' ho boletse Philippe Damier, hlooho ea lefapha la methapo ea mafu sepetleleng sa Nantes CHU. Jambart o ile a fuoa meriana e fapaneng mme mathata a hae a nyamela. O itse: 'Ntle ho moo, nka be ke ipolaile kapa nka be ke ile teronkong.'
Litefiso tsa tefo Brithani li phatlalalitsoe khoeling e fetileng ke bakuli ba babeli ba Parkinson ba ipolelang hore ba fetohile makhoba a papali ea chelete kamora ho fuoa Mirapexin.
Sehlooho se Original
Graham Tearse a Nantes
Sontaha sa December 9, 2007
The Observer
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