Biol Psychiatry. 2015 Nov 17. pii: S0006-3223 (15) 00954-3. Doi: 10.1016 / j.biopsych.2015.10.024.
Kwako LE1, Mosali R2, Litten RZ3, Koob GF4, Goldman D5.
inahaneloang
Sengoloa sena se hlahisa moralo oa heuristic bakeng sa Tlhatlhobo ea Addictions Neuroclinical e kenyelletsang likarolo tsa bohlokoa tsa ts'ebetso tse tsoang ho li-neurocircuitry tsa bokhoba. Re lekola hore na mathata a ho lemalla (ADs) a fumaneha joang hona joale le tlhoko ea mehato e mecha ea neuroclinical ea ho khetholla bakuli ba fihlelang litekanyetso tsa kliniki ea ho lemalla moemeli a le mong ha ba fapana ho etiology, ramatiki le karabelo ea kalafo. Tlhokahalo ea kutlwisiso e ntlafalitsoeng ea mekhoa e hlasimollang le ho boloka bokhoba, joalo ka ha ho pakoa ke meeli ea kalafo ea hajoale le tlhahlobo ea kalafo ea kalafo ea bongaka, e hlalositsoe. Ntle le moo, ho hlalositsoe liphetoho tsa morao-rao ho nalology ea AD, liphephetso lits'ebetsong tsa mekhahlelo ea hona joale, le liteko tsa pele tsa ho nyenyefatsa batho ba nang le li-AD. Maiteko a tlatselletsang, ho kenyelletsa morero oa Research Domain Criteria, o entseng melaoana ea ts'ebetso ea methapo ea mafu a kelello e tšohloa. Mesebetsi e meraro-kholo ea ts'ebetso, ts'usumetso ea ts'usumetso, le maikutlo a mabe-a hokahane le mekhahlelo e fapaneng mokhatlong oa tšebeliso ea litheko li etsa likarolo tsa mantlha tse sebetsang tsa li-AD. Tekanyo ea libaka tsena lithutong tsa lefu la mafu a lefutso, liphatsa tsa lefutso, tsa bongaka le tsa kalafo li tla fana ka litlatsetso bakeng sa kutloisiso ea batho ba arohaneng le phapang ea nakoana lithutong, mehato e arolelanoang mathateng a tlatsetsang, tšusumetso ea ho fetoha ha tšusumetso ea tikoloho le boitsebahatso ba mofuta. Kamora nako, re bonts'a hore hoa bohlokoa ho kenya tšebetsong tlhatlhobo e tebileng joalo ea methapo u sebelisa motsoako oa mekhoa ea ts'ebetso le ts'ebetso. Tlhahlobo ea Neuroclinical ke senotlolo sa ho boelanya "nalology" ea li-AD motheong oa ts'ebetso le etiology, tsoelo-pele e ka lebisang ho ntlafatsong ea thibelo le kalafo.
LINKOTSO: Tlatsetso; Tlhahlobo; Boloetse: Neuroimaging; Nosology; Ts'ebeliso ea lithethefatsi
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