Khopolo-taba. 2012 Jun 1;211:107-25. doi: 10.1016/j.neuroscience.2011.08.014.
Ahmed SH1.
inahaneloang
Patlisiso e kenyeletsang mefuta ea liphoofolo tsa bokhoba ba lithethefatsi e ka bonoa e le mofuta o mong oa maikutlo a fapaneng. Ho fapana le lingaka tse batlang ho phekola batho ba lemaletseng lithethefatsi hore li se ke tsa hlola li ts'oaroa, bafuputsi ba batla ho etsa liphoofolo tse lemaletseng lithethefatsi hore li lemaletse lithethefatsi tse nang le thepa e tsebahalang ea ho lemalla ho batho. Maikemisetso a lipatlisiso tsena ke ho utloisisa hamolemo letsoalo la bokhoba ba lithethefatsi, 'me qetellong, ho fetolela tsebo ena ho kalafo e sebetsang bakeng sa batho ba lemaletseng. Tlhahlobo ea hona joale e ke ke ea akaretsa lingoliloeng tse kholo tse bokelletseng lilemong tse fetileng tsa 50 ka mefuta ea liphoofolo tse lemalloang ke lithethefatsi. Ho sa le joalo e sebelisitsoe ka boinyenyefatso ho feta lipatlisiso tsa morao-rao tse mabapi le litekanyetso tse ipehang tsa taolo ea lithethefatsi ho rat (mefuta ea liphoofolo e sebelisoang khafetsa tšimong), e shebane haholo le boiteko ba hajoale ba ho etsa tšebeliso ea koae ka thata. khahlanong le ts'ebeliso e se nang lithibelo. Ho makatsang ke hore, ho latela hore tšebeliso ea k'hok'heine e qobelloang ka har'a likhoto e ea khonahala empa ho thata ho feta kamoo ho neng ho hopotsoe pele. Ebile, ho bonahala eka ho iphetetsa ho lemaletseng koae ke ntho e tloaelehileng literekeng. Joalo ka ho basebelisi ba koae ba batho, ke likhoto tse 'maloa feela tse ka bang kotsing. Qeto ena e na le litlamorao tse ngata tsa bohlokoa lipatlisiso tsa nako e tlang mabapi le bokhoba ba tahi ea koae le tsoelo-pele ea meriana ea preclinical.
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