Should compulsive sexual behavior be considered an addiction? (2016)

COMMENTS: This paper was published under the “Debate” category in the journal ‘Addiction‘. Its main weakness is that it purports to address compulsive sexual behavior (CSB), an umbrella term that covers everything sexual. For example, “CSB” can encompass hypersexuality or “sex addiction” and may include such behaviors as serial infidelity or acting out with prostitutes. […]

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Dopamine cross-sensitization between psychostimulant drugs and stress in healthy male volunteers (2016)

Citation: Translational Psychiatry (2016) 6, e740; doi:10.1038/tp.2016.6 Published online 23 February 2016 L Booij1,2,3,10, K Welfeld3,10, M Leyton3,4,5, A Dagher5, I Boileau6, I Sibon7, G B Baker8, M Diksic5, J-P Soucy5, J C Pruessner9, E Cawley-Fiset3, K F Casey2 and C Benkelfat3,5 1Department of Psychology, Concordia University, Montreal, QC, Canada 2CHU Sainte Justine Hospital Research Center, University of Montreal, Montreal, QC, Canada 3Department of Psychiatry, McGill University, Montreal, QC, Canada […]

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Stable immediate early gene expression patterns in medial prefrontal cortex and striatum after long-term cocaine self-administration (2015)

Addict Biol. 2015 Nov 24. doi: 10.1111/adb.12330. Gao P1, Limpens JH2, Spijker S3, Vanderschuren LJ2,4, Voorn P1. Abstract The transition from casual to compulsive drug use is thought to occur as a consequence of repeated drug taking leading to neuroadaptive changes in brain circuitry involved in emotion and cognition. At the basis of such neuroadaptations […]

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Consumption of palatable food primes food approach behavior by rapidly increasing synaptic density in the VTA (2016)

Proc Natl Acad Sci U S A. 2016 Feb 16. pii: 201515724. Liu S1, Globa AK2, Mills F2, Naef L1, Qiao M1, Bamji SX2, Borgland SL3. FULL STUDY – PDF Abstract In an environment with easy access to highly palatable and energy-dense food, food-related cues drive food-seeking regardless of satiety, an effect that can lead […]

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Dorsal Striatal Dopamine, Food Preference and Health Perception in Humans (2014)

PLoS One. 2014; 9(5): e96319. Published online 2014 May 7. doi:  10.1371/journal.pone.0096319 PMCID: PMC4012945 Deanna L. Wallace,1,* Esther Aarts,1,2 Linh C. Dang,1,3 Stephanie M. Greer,1 William J. Jagust,1 and Mark D′Esposito1 J. Bruce Morton, Editor Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in […]

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Dopamine ups and downs in vulnerability to addictions: a neurodevelopmental model (2014)

Trends Pharmacol Sci. Author manuscript; available in PMC 2015 Jun 1. Published in final edited form as: Trends Pharmacol Sci. 2014 Jun; 35(6): 268–276. Published online 2014 Apr 30. doi:  10.1016/j.tips.2014.04.002 PMCID: PMC4041845 NIHMSID: NIHMS585222 Marco Leyton, Ph.D.1,2,3,4,* and Paul Vezina, Ph.D.5,6 Author information ► Copyright and License information ► The publisher’s final edited version […]

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