Age 22 – PIED: My sex drive is back, my sex life is healthy, and I am so happy that I changed my life

I am 400 days porn free and feel better than I ever have before. I used to have stone-cold PIED, and it is markedly improved. I’ve ditched so much dead weight by not letting myself watch porn all the time and I can now enjoy the things that I am supposed to be able to. […]

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Epigenetic and Proteomic Expression Changes Promoted by Eating Addictive-like Behavior (2015)

Neuropsychopharmacology. 2015 May 6. doi: 10.1038/npp.2015.129. Mancino S1, Burokas A1, Gutiérrez-Cuesta J1, Gutiérrez-Martos M1, Martín-García E1, Pucci M2, Falconi A2, D’Addario C3, Maccarrone M4, Maldonado R1. Abstract An increasing perspective conceptualizes obesity and overeating as disorders related to addictive-like processes that could share common neurobiological mechanisms. In the present study, we aimed at validating an […]

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Spatiotemporal dynamics of dendritic spines in the living brain (2014)

Chia-Chien Chen,1 Ju Lu,2 and Yi Zuo1,* 1Department of Molecular, Cell and Developmental Biology, University of California at Santa Cruz, Santa Cruz, CA, USA 2Department of Biological Sciences and James H. Clark Center, Stanford University, Stanford, CA, USA Mini Review ARTICLE Front. Neuroanat., 09 May 2014 | doi: 10.3389/fnana.2014.00028 Abstract Dendritic spines are ubiquitous postsynaptic […]

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Caffeine increases striatal dopamine D2/D3 receptor availability in the human brain (2015)

Citation: Translational Psychiatry (2015) 5, e549; doi:10.1038/tp.2015.46 Published online 14 April 2015 N D Volkow1, G-J Wang1, J Logan2, D Alexoff2, J S Fowler2, P K Thanos2, C Wong1, V Casado3, S Ferre4 and D Tomasi1 1Intramural Research Program, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, USA 2Brookhaven National Laboratory, Upton, NY, USA 3Department of Biochemistry and Molecular Biology, University of Barcelona, Barcelona, Spain 4Intramural […]

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Obesity Is Associated with Decreased μ-Opioid But Unaltered Dopamine D2 Receptor Availability in the Brain (2015)

Comments: Earlier animal studies show a loss of D2 receptors cause by overeating, and human studies show an increase of dopamine D2 receptors when obese patients lose weight. This isn’t settled. LINK TO ABSTRACT Henry K. Karlsson1, Lauri Tuominen1,2, Jetro J. Tuulari1, Jussi Hirvonen1,3, Riitta Parkkola3, Semi Helin1, Paulina Salminen4, Pirjo Nuutila1,5, and Lauri Nummenmaa1,6 […]

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