Neuropharmacology. 2014 Feb;77:224-33. doi: 10.1016/j.neuropharm.2013.09.019. Lazenka MF1, Selley DE1, Sim-Selley LJ2. Abstract Repeated Δ(9)-tetrahydrocannabinol (THC) administration produces desensitization and downregulation of cannabinoid type 1 receptors (CB₁Rs) in the brain, but the magnitude of these adaptations varies among regions. CB₁Rs in the striatum and its output regions exhibit the least magnitude and slowest development of desensitization […]
Read More… from DeltaFosB induction correlates inversely with CB₁ receptor desensitization in a brain region-dependent manner following repeated Δ⁹-THC administration (2014)
Addict Biol. Oct 2010; 15(4): 491–503. doi: 10.1111/j.1369-1600.2010.00242.x Anna E Goudriaan,1,2 Michiel B de Ruiter,1,3 Wim van den Brink,1,2 Jaap Oosterlaan,4 and Dick J Veltman1,3 Author information ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract Abnormal cue reactivity is a central characteristic of […]
Read More… from Brain activation patterns associated with cue reactivity and craving in abstinent problem gamblers, heavy smokers and healthy controls: an fMRI study (2010)
Before this streak of 77 days or whatever I’m on, I had been relapsing pretty badly, I even wrote in my journal about it. I’d completely fallen off the wagon and was in a general spiral of self destruction and malcontent. I know we’ve all been there so I will spare the details :p. I […]
Read More… from Age 25 – (ED) The change in myself has been jaw-dropping
PLoS One. 2014 Jul 7;9(7):e101585. doi: 10.1371/journal.pone.0101585. Wang GJ1, Tomasi D1, Convit A2, Logan J3, Wong CT1, Shumay E1, Fowler JS4, Volkow ND1. Abstract Objective Dopamine mediates the rewarding effects of food that can lead to overeating and obesity, which then trigger metabolic neuroadaptations that further perpetuate excessive food consumption. We tested the hypothesis that […]
Read More… from BMI Modulates Calorie-Dependent Dopamine Changes in Accumbens from Glucose Intake (2014)
So I finally made it 90 days. I wanted to to weigh in on my experience. This is absolutely worth it and completely changed my life! I’ve been attempting this for 2.5 years. Background – My previous furthest streak was 62 days (twice), but this was by far one of the hardest challenges of my […]
Read More… from ED & brain fog cured, Social anxiety almost gone, Increased motivation & energy
Neurology Now: Paturel, Amy M.S., M.P.H. June/July 2014 – Volume 10 – Issue 3 – p 32-36 doi: 10.1097/01.NNN.0000451325.82915.1d At age 17, Anthony Rosner of London, England, was a hero in the World of Warcraft online gaming community. He built empires, led raids, and submerged himself in a fantasy world that seemingly fulfilled his every […]
Read More… from Game Theory: How do video games affect the developing brains of children and teens? (2014)
6 years I have been training boxing and bodybuilding. I have never got any muscularity or veiny hands. After 10 months of NoFap attempts (longest 39 days streak) I have made the body I always dreamed of! My legs are finally thinner than my waist. My back and shoulder and arms are lean and bigger […]
Read More… from Age 21 – Why has my body changed so much after 10 months?
Am J Clin Nutr. 2013 Jun;97(6):1188-94. doi: 10.3945/ajcn.112.055285. Epub 2013 Apr 17. Burger KS1, Stice E. Author information Abstract Background: Obese compared with lean individuals show greater attention-, gustatory-, and reward-region responsivity to food cues but reduced reward-region responsivity during food intake. However, to our knowledge, research has not tested whether an objectively measured caloric […]
Read More… from Elevated energy intake is correlated with hyperresponsivity in attentional, gustatory, and reward brain regions while anticipating palatable food receipt (2013)
If you watch a lot of soft porn, you may want more extreme stuff in the future. Porn, suggests a new study, influences the structure of your brain: in fact, it might even make your brain shrink. Men who watch large amounts of sexually explicit material have brains with smaller reward systems, a study finds. […]
Read More… from Watching Internet porn will wear out your brain and make it shrivel (first brain scan study published on porn users), 5/28/2014
Med Sci Sports Exerc. 2014 May 12. [Epub ahead of print] Choi JW1, Han DH, Kang KD, Jung HY, Renshaw PF. Author information Abstract PURPOSE: As adjuvant therapy for enhancing the effects of stimulants and thereby minimizing medication doses, we hypothesized that aerobic exercise might be an effective adjunctive therapy for enhancing the effects of […]
Read More… from Aerobic Exercise and Attention Deficit Hyperactivity Disorder: Brain Research (2014)