Age 36 – I just made love successfully for 30 minutes after almost 2 years of suffering PIED.

I’m 36 years old with around 20 years of use, so sure, I had some improvements but I’d probably need a couple of years to clean most of the past bad habits. So the first lesson here is, especially for younger people, don’t delay the recovery anymore, later is worse. To the point, what I […]

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The behavioral pharmacology of effort-related choice behavior: dopamine, adenosine and beyond (2012)

J Exp Anal Behav. 2012 Jan;97(1):125-46. doi: 10.1901/jeab.2012.97-125. Salamone JD1, Correa M, Nunes EJ, Randall PA, Pardo M. Abstract For many years, it has been suggested that drugs that interfere with dopamine (DA) transmission alter the “rewarding” impact of primary reinforcers such as food. Research and theory related to the functions of mesolimbic DA are […]

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Divergent circuitry underlying food reward and intake effects of ghrelin: dopaminergic VTA-accumbens projection mediates ghrelin’s effect on food reward but not food intake (2013)

Neuropharmacology. 2013 Oct;73:274-83. doi: 10.1016/j.neuropharm.2013.06.004. Epub 2013 Jun 14. Skibicka KP1, Shirazi RH, Rabasa-Papio C, Alvarez-Crespo M, Neuber C, Vogel H, Dickson SL. Abstract Obesity has reached global epidemic proportions and creating an urgent need to understand mechanisms underlying excessive and uncontrolled food intake. Ghrelin, the only known circulating orexigenic hormone, potently increases food reward […]

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The clinical relevance of neuroplasticity in corticostriatal networks during operant learning (2013)

Neurosci Biobehav Rev. Author manuscript; available in PMC 2014 Nov 1. Published in final edited form as: Neurosci Biobehav Rev. 2013 Nov; 37(0): 10.1016/j.neubiorev.2013.03.019. Published online 2013 Apr 5. doi:  10.1016/j.neubiorev.2013.03.019 PMCID: PMC3830626 NIHMSID: NIHMS464960 Matthew E. Andrzejewski,1 Brenda L. McKee,2 Anne E. Baldwin,3 Lindsay Burns,4 and Pepe Hernandez4 Author information ► Copyright and License […]

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Altered resting-state functional connectivity of the insula in young adults with Internet gaming disorder (2015)

Addict Biol. 2015 Apr 20. doi: 10.1111/adb.12247. Zhang JT1, Yao YW, Li CS, Zang YF, Shen ZJ, Liu L, Wang LJ, Liu B, Fang XY. Abstract The insula has been implicated in salience processing, craving, and interoception, all of which are critical to the clinical manifestations of drug and behavioral addiction. In this functional magnetic […]

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Review Article: Molecular and Functional Imaging of Internet Addiction (2015))

Biomed Res Int. 2015;2015:378675. Epub 2015 Mar 24. Zhu Y1, Zhang H1, Tian M1. Volume 2015 (2015), Article ID 378675, 9 pages http://dx.doi.org/10.1155/2015/378675 Yunqi Zhu,1,2,3,4 Hong Zhang,1,2,3,4 and Mei Tian1,2,3,4 1Department of Nuclear Medicine, The Second Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, Zhejiang 310009, China 2Zhejiang University Medical PET Center, […]

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Increased corticolimbic connectivity in cocaine dependence versus pathological gambling is associated with drug severity and emotion-related impulsivity (2015)

Addict Biol. 2015 Mar 29. doi: 10.1111/adb.12242. Contreras-Rodríguez O1, Albein-Urios N, Vilar-López R, Perales JC, Martínez-Gonzalez JM, Fernández-Serrano MJ, Lozano-Rojas O, Clark L, Verdejo-García A. Abstract Neural biomarkers for the active detrimental effects of cocaine dependence (CD) are lacking. Direct comparisons of brain connectivity in cocaine-targeted networks between CD and behavioural addictions (i.e. pathological gambling, […]

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