Reward Mechanisms in Obesity: New Insights and Future Directions (2011)

 COMMENTS: a review by the top researcher on obesity and food addiction. FULL STUDY Volume 69, Issue 4, 24 February 2011, Pages 664–679 http://dx.doi.org/10.1016/j.neuron.2011.02.016, Review Paul J. Kenny1, , 1 Laboratory of Behavioral and Molecular Neuroscience, Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, FL 33458, USA ________________________________________ Food is consumed in order to maintain […]

Read More… from Reward Mechanisms in Obesity: New Insights and Future Directions (2011)

DeltaFosB in the Nucleus Accumbens Regulates Food Reinforced Instrumental Behavior and Motivation (2006)

FULL STUDY The Journal of Neuroscience, 6 September 2006, 26(36): 9196-9204; doi: 10.1523/JNEUROSCI.1124-06.2006 Peter Olausson1, J. David Jentsch2, Natalie Tronson1, Rachel L. Neve3, Eric J. Nestler4, and Jane R. Taylor1 1.Correspondence should be addressed to Jane R. Taylor, Department of Psychiatry, Division of Molecular Psychiatry, Yale University School of Medicine, Ribicoff Research Facilities, Connecticut Mental […]

Read More… from DeltaFosB in the Nucleus Accumbens Regulates Food Reinforced Instrumental Behavior and Motivation (2006)

DeltaFosB: A sustained molecular switch for addiction (2001)

COMMENTS: As later studies will reveal DeltaFosB is the common molecular switch for both drug and behavioral addictions. It’s a transcription factor which means it affects what genes are turned on or off. As stated elsewhere, addictive drugs only hijack normal mechanisms. That’s why it’s silly to suggest that behavioral addictions cannot exist.  FULL STUDY […]

Read More… from DeltaFosB: A sustained molecular switch for addiction (2001)

Age 42 – 90 days and karezza

tl; dr: Karezza saved my relationship. I came to this place via karezza. Last fall, while hanging out in /r/deadbedrooms, I came across some articles by Marnia Robinson, in particular this one, that suggested to me that my focus on sex was possibly the reason why I didn’t get any in my long-term relationship. So […]

Read More… from Age 42 – 90 days and karezza

Another angle on the science behind the flatline

This scientist doesn’t speak in terms of addiction-related changes, but he describes how learning changes the brain. Addiction is pathological learning. This exchange appeared on Reddit.com under “AskScience.” Why does abstaining from porn/masturbation/orgasm temporarily decrease as opposed to increase libido? In /r/nofap there’s a move to ‘reboot’ one’s overstimulated brain to restore the sensitivity to […]

Read More… from Another angle on the science behind the flatline

Age 32 – Married, German

Day 33 I’m from Germany. I am 32 and what you would probably call a very good looking guy. I’m married to a beautiful woman and I work in the central department of a world famous company. Before that I had finished high school with a A+ degree (called 1,0 Abitur in Germany) and then […]

Read More… from Age 32 – Married, German