UHorm Behav. 2013 Jul;64(2):203-10. doi: 10.1016/j.yhbeh.2013.05.010.
Juraska JM, Sisk CL, UDoncarlos LL.
imvelaphi
ISebe leNkqubo yeNgqondo yeNgqondo kunye neNeuroscience, iYunivesithi yase-Illinois, 603 E Daniel St., Champaign, IL 61820, eUnited States. Idilesi yombane: [imeyile ikhuselwe].
Abstract
Eli nqaku liyinxalenye yoMba oKhethekileyo othi "Ukufikisa nokuQala". Ukwahlula ngokwesondo yinkqubo apho inkqubo ye-nervous iguquka ngokwesakhiwo kwaye isebenze ngokungafaniyo kwabasetyhini kunye namadoda. Kwizilwanyana ezanyisayo, le nkqubo kucingelwa ukuba yenzeke ngexesha lokubeleka kwangaphambi kokubeleka kunye nophuhliso lwasemva kokubeleka, xa ukonyuka okwethutyana kwi-testosterone secretion yenza ubudoda kwaye yenze isidima senkqubo yemithambo-luvo ekhulayo yamadoda. Amashumi eminyaka ophando akhokelele kwiimbono zokuba i-dimorphisms yezesondo eyenziwe ngexesha lokukhula kwe-perinatal igcinwa ngokuqhubekayo kubomi bonke, kwaye iihomoni ze-ovarian azidlali indima esebenzayo ekwenzeni inkqubo ye-nervous yabasetyhini. Ngapha koko, i-testosterone ye-perinatal yayicingelwa ukuba imisele umahluko ngokwesondo kwinombolo ye-neuron ngokulawula ukufa kweeseli kunye nokusinda kweeseli, kwaye hayi ngokulawula ukwanda kweeseli. Njengoko uphando lophuhliso lwe-neural ngexesha lokufikisa luye lwabonakala ngakumbi ngasekupheleni kwenkulungwane yama-20 kwaye lwatyhila ubungakanani bohlengahlengiso lobuchopho ngeli xesha, nganye yezi mfundiso iye yacelwa umngeni kwaye yalungiswa. Apha sihlaziya ubungqina obuvela kwiincwadi zezilwanyana ukuba i-1) ingqondo iphinda ihluke ngokwesondo ngexesha lokufikisa kunye nokufikisa; 2) iihomoni ze-ovarian zidlala indima esebenzayo kwi-feminization yengqondo ngexesha lokufikisa; kunye ne-3) imodyuli yehomoni, ukongezwa okuthe ngqo kwezesondo kwi-neuron ezintsha kunye neeseli ze-glial, kunye nokulahleka kwee-neuron, kufaka isandla ekwahlulweni ngokwesondo kwe-hypothalamic, i-limbic, kunye nemimandla ye-cortical ngexesha lokufikisa. Olu hlengahlengiso loyilo ngexesha lenqanaba lokufikisa lokwahlulahlula ngokwesondo kwengqondo kunokuthi kube phantsi kweyantlukwano yezesondo eyaziwayo ekubeni sesichengeni kumlutha kunye nokuphazamiseka kwengqondo okuvela ngeli xesha lophuhliso.
Ilungelo lokushicilela X XUMUM Elsevier Inc.
IINKCUKACHA:
Ubutsha, i-Amygdala, Ukufa kweeseli, iCortex, iihomoni ze-Gonadal steroid, i-Hypothalamus, i-Myelination, i-Neurogenesis, Ukufikisa, Umahluko ngokwesondo
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