Front Endocrinol (Lausanne). I-2018 Nov 9; 9: 661. doi: 10.3389 / fendo.2018.00661. eCollection 2018.
Nelder M1, Ukucoca uF1, UZhang H1, UZhai G1, Gulliver W1, UTeng W2, Shan Z2, Ilanga G1.
Abstract
imvelaphi: Isifundo sethu sangaphambilini se-29 yeziyobisi zokutya ezi-feta ze-XNUMX zifumanise ukuba i-FA inxulumene neeprofayili ze-lipid kunye namahomoni anokuthi abe yinto yesifo sentliziyo (CVD) kunye ne-insulin ukumelana. Nangona kunjalo, okwangoku akukho datha ekhoyo ngokubhekisele kubudlelwane phakathi kweempawu ze-FA kunye neempawu ze-metabolic zeCVD kunye ne-IR kubantu ngokubanzi. Sisilungiselele olu phando ukuba luphande ukunxibelelana phakathi kweempawu ze-FA kunye neeprofayili ze-lipid kunye ne-IR kumadoda nabafazi bebonke baseNewfoundland.
Iindlela: Abantu be-710 (abasetyhini be-435 kunye namadoda angama-275) abagqityiweyo ukusuka kubemi baseNewfoundland ngokubanzi basetyenziswa kuhlalutyo. Iimpawu ze-FA zavavanywa kusetyenziswa i-Yale Food Addiction Scale (YFAS). Iglucose, i-insulin, i-HDL, i-LDL, i-cholesterol iyonke kunye namanqanaba e-triglycerides athelekiswa. I-IR yavavanywa kusetyenziswa imodeli ye-homeostatic yovavanyo (HOMA). Abathathi-nxaxheba bahlelwe ngokwabelana ngesondo kunye nesimo sokuya esikhathini. Iminyaka yobudala, imisebenzi yomzimba, iikhalori kunye neepesenti eziphelele zomzimba zazilawulwa.
iziphumo: Uhlalutyo oluhambelana nolungelelwaniso luveze ukuba emadodeni, ukubalwa kweempawu ze-YFAS kulungelelaniswe kakhulu ne-HOMA-β (r = 0.196, p = 0.021), triglycerides (r = 0.140, p = 0.025) kunye nokunxibelelana ngaphakathi ne-HDL (r = -0.133, p = 0.033). Emva kokwahlula-hlula ngokwesimo sokuya menopausal, abasetyhini abangaphambi kokuya esikhathini baye babonisa akukho lungelelwaniso kwaye abasetyhini abangamadoda emva kokuya esikhathini banokubaluleka okukhulu nge-triglycerides (r = 0.198, p = 0.016).
Isiphelo: I-FA idityaniswa ngokubonakalayo nemiphawu eliqela yokuphazamiseka kwe-metabolic emadodeni kunye nomncinci, abafazi abahamba emva kokuya esikhathini, kubantu ngokubanzi. Uphando olongezelelekileyo luyafuneka ukucacisa ubudlelwane obuthile bezesondo kunye nokucacisa naziphi na iindlela ezinokubangela ukungqinelani.
IINJONGO ZOKUGQIBELA: iziyobisi ukumelana ne-insulin; i-lipids; ukutyeba kakhulu; inqanaba lokutya okuneziyobisi
PMID: 30473679
PMCID: PMC6237829
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