Neuropsychopharmacology. 2000 Jun;22(6):581-94.
Rob Robes AJ1, Heyser CJ, Cole M, U-Griffin P, Koob GF.
Abstract
Iimpawu zokurhoxiswa kotywala, ngakumbi imeko yeemvakalelo ezimbi, inokuqhubeka iinyanga emva kokususwa kotywala. Ezi mpawu zihambisayo zokurhoxa zibekhona njengesixhobo esibalulekileyo sokubuyela ekuseleni kakhulu kwiziselo ezinxilisayo kwaye sinokumela utshintsho olude lwethoni ehambelana nesiphumo sokuvezwa kotywala okungapheliyo. Kwaboniswa ngaphambili ukuba iigundane ezixhomekeke kwi-ethanol zonyusa umsebenzi wazo ekuphenduleni i-ethanol xa ihlolwe ngexesha le-12 hr yokuqala emva kokurhoxiswa. Injongo yoluvavanyo lwangoku yayikukufumanisa ukuqhubeka komkhangeli ngokuhlola ulawulo lwe-ethanol yomlomo kwi-rats enembali yokuxhomekeka komzimba kwi-ethanol, i-detoxified kwaye ke ivumele ithuba leeveki ezimbini zokurhoxiswa okungafunekiyo. Iziphumo zolu vavanyo zibonisa ukuba ukuphendula okusebenzayo kwe-ethanol kwaphuhliswa ngexesha lokukhutshelwa ngaphandle kwe-30-100% kwaye yahlala iphakanyisiwe kwiiveki ze-4-8 emva kokurhoxiswa okunamandla. Ezi ziphumo zinefuthe elibalulekileyo lokuqonda iimpawu kunye neendlela eziphantsi kokuba sesichengeni sokubuyela umva.
PMID: 10788758
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