Iprog Brain Res. 2012;198:65-77. doi: 10.1016/B978-0-444-59489-1.00006-9.
Abstract
I-Orexin, ekwabizwa ngokuba yi-hypocretin, yi-hypothalamic neuropeptide ebalulekileyo yokulamla kunye nokulala kunye nokondla kunye namandla e-homeostasis. Izifundo zamva nje zibonakalise ukuba i-orexin ikwadlala indima ephambili yokulawula inkuthazo kunye nomvuzo onxulumene nokutya kunye neziyobisi zokuxhatshazwa. Ngokusekwe kwezo zinto zifunyanisiweyo, kuye kwaqinisekiswa ukuba i-orexin iyabandakanyeka kulawulo lwezinye iindlela zokuziphatha zomvuzo. Olu hlaziyo luza kushwankathela izifundo ezihlola indima ye-orexin kwisishukumiso kunye nomvuzo onxulunyaniswa nokutya, ukuziphatha koomama, kunye nokuziphatha ngokwesondo kwamadoda. Ngokukodwa ekuziphatheni ngokwesondo kwiigundane zesilisa, kutshanje sibonisile ukuba izilonda ezikhethekileyo zeseli azikukhathazi ukusebenza ngokwesondo kunye nokukhuthaza kodwa ziphazamise iimpendulo ezihambelana nomvuzo wesondo.
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