IZIMPENDULO: Ngenkathi leli phepha liyincwadi nje emfushane, liqukethe ukubukelwa okumbalwa kwesayensi yokuqhamuka. Ukwenza isibonelo, kusho ukuthi zombili Prause et al., 2015 futhi Kuhn & Gallinat, 2014 kubika okutholayo okufanayo: ukusetshenziswa okukhulu kwe-porn okuhambisana nokujwayela okukhulu kwezocansi. Zombili izifundo zabikwa aphansi ukuvuselelwa kobuchopho ekuphenduleni ukufinyelelwa okufutshane kwezithombe ze-porno ye-vanilla. Esikhathini esilandelayo "I-Lower-positive-potentially" ibhekisela ekutholeni kwe-EEG Prause et al.:
"Ngokungqubuzanayo, Ucwaningo lwabantu abanempilo luphakamisa indima yokwenza ngcono ukujwayela nokusebenzisa ngokweqile izithombe zobulili ezingcolile. Emadodeni enempilo, isikhathi esengeziwe sichithwa ukubukela izithombe zobulili ezingcolile ezihambisana nomsebenzi we-putaminal ophansi ngezithombe ezingcolile (Kühn noGallinat, 2014). Umsebenzi osezingeni eliphansi ongakwenza kahle ezithombeni ezinezithombe zobulili ezingcolile kwakubhekwa ezihlokweni ezazinenkinga yokusebenzisa izithombe zobulili ezingcolile. ”
Kungani lokhu kubalulekile? Umlobi oholayo uNicole Prause wathi isifundo sakhe se-EEG esisodwa senza "umlutha wezocansi". Leli yiphepha lesibili elibukeziwe kontanga lokwenqaba ukutolika kukaPrause. Nakhu iphepha lokuqala.
Qaphela - Amanye amaphepha amaningi abuyekezwe ngontanga avuma lokho Prause et al., 2015 isekela imodeli yokulutha kabi kocansi: Izibukezo ezibuyekezwa kontanga Prause et al., 2015
I-Neuropsychopharmacology 41, 385-386 (Januwari 2016) | ezimbili: 10.1038 / npp.2015.300
Shane W Kraus 1, 2, Valerie Voon 3, noMarc N Potenza 2, 4
I-1 VISN I-1 Ukugula Kwengqondo Imfundo Yokucwaninga Nezikhungo Zomtholampilo, uhlelo lwe-VA lwezempilo lwe-Connecticut, West Haven, CT, USA; Umnyango we-Psychiatry we-2, i-Yale University School of Medicine, eNew Haven, CT, eU.SA;
Umnyango we-Psychiatry we-3, iYunivesithi yaseCambridge, eCambridge, UK;
Umnyango we-Neurobiology we-4, i-Child Study Center ne-CASA Columbia, Yale University School of Medicine, eNew Haven, CT, eU.SA
E-mail: [i-imeyili ivikelwe]
Ukuziphatha kocansi okuphoqelekile (CSB) kubonakala ngokufisa, ukungabi nomqondo, ukukhubazeka komphakathi / emsebenzini, nokuncintisana kwengqondo. Ukuqhathaniswa kwe-CSB kulinganiselwa cishe kwe-3-6%, enezikhulu zesilisa. Nakuba kungahlanganisiwe ku-DSM-5, i-CSB ingatholakaliswa ku-ICD-10 njengesifo sokulawula ukucindezela. Kodwa-ke, ingxabano ikhona mayelana nokuhlelwa kwe-CSB (isib., Njengesifo esiyinkimbinkimbi-yokucindezeleka, isici sokuxilongwa ngokobulili, ukubheja ngokweqile, noma ukuhambisana nokuqhubeka komkhuba wokuziphatha ngokocansi).
Ubufakazi bokuqala bukhombisa ukuthi i-dopamine ingabamba iqhaza kwi-CSB. Esigungwini sikaParkinson (PD), izifo zokwelapha ezibizwa ngokuthi i-dopamine (Levo-dopa, i-dopamine agonists) ziye zahlotshaniswa ne-CSB nezinye izifo zokulawula ukucindezeleka (Weintraub et al, 2010). Inombolo encane yezifundo ze-case usebenzisa i-naltrexone ukwesekwa kwayo ekunciphiseni izikhalo nokuziphatha okuhambisana ne-CSB (i-Raymond et al, i-2010), ehambisana nokuguqulwa kwe-opioidergic ye-mesolimbic dopamine umsebenzi ekunciphiseni i-CSB. Njengamanje, ukuhlolwa kwamaphesenti amakhulu, okunamandla, okwenziwe ngokwanele, okuhlolwayo kwegazi kuyadingeka ukuze kuqhutshekwe ukuqonda i-CSB.
Izinyathelo zokugqugquzela ezokugqugquzela zihlobene nokucutshungulwa kocansi. Ama-CSB namadoda angewona ama-CSB abe nokusebenza okukhulu kwe-sex-cuerelated ye-anterior cingulate, i-ventral striatum, ne-amygdala (Voon et al, 2014). Kwizihloko ze-CSB, ukuxhumana okusebenzayo kwalenethiwekhi okuhlotshaniswa nesifiso socansi oluhlobene nesicingo, ngaleyo ndlela kubhekisana nokuthola izidakamizwa ezidakamizwa (i-Voon et al, i-2014). Amadoda e-CSB aqhubeka nokukhombisa ukugxila okubhekiswe ekuziqapheleni kwezithombe zobulili ezingcolile, okubandakanya izimpendulo zakuqala zokubheka njengokwezidakamizwa (Mechelmans et al, 2014). Ezikhathini ze-CSB neziguli ze-PDB ezingekho CSB, ukuvezwa kwezithombe zobulili ezingcolile kwandise ukusebenza ku-stroke, ukuxhuma kanye ne-orbitofrontal cortex, nokuxhumanisa nesifiso socansi (Politis et al, 2013). Ukutadisha okuncane kwe-imaging-tensor okufisa ukuxuba kubandakanya ukungalingani okungajwayelekile kwi-CSB namadoda angewona ama-CSB (i-Miner et al, i-2009).
Ngokuphambene, ucwaningo kubantu abaphilile bancomela iqhaza lendlu eyenzelwe ukuthuthukisa ukusetshenziswa kwezithombe zocansi ngokweqile. Emadodeni aphile kahle, isikhathi esandisiwe esichithwa sibuka izithombe ezingcolile zihambisana nomsebenzi ongaphansi wesobunxele ezithombeni zobulili ezingcolile (uKühn noGallinat, 2014). Umsebenzi ophansi ongabikhona ongatheni ezithombeni zobulili ezingcolile wabonwa ngezihloko ezinenkinga yokusebenzisa izithombe zobulili ezingcolile. Lokhu okutholakele, kuyilapho kuqhathaniswa, akuhambisani. Ukujwayeleka kwezingcaphuno zesithombe ezihlobene namavidiyo angathuthukiswa kubantu abanempilo ngokusebenzisa ngokweqile; kuyilapho, izihloko ze-CSB ezinokusetshenziswa kakhudlwana / ezinamandla zingase zithuthukise ukucubungula.
Yize ucwaningo lwamuva lwama-neurobiological luye lwaphakamisa izindlela ezithile ze-neurobiological ze-CSB, lezi zindlela kufanele ziphathwe njengezindlela ezithintekayo ezihlinzekwa ukulinganiselwa kwezindlela (isib. Amasayizi amancane esampula, imiklamo ehlukene, izihloko zesilisa kuphela, njalonjalo). Izikhala zamanje zocwaningo zikhona eziphoqelela ukuzimisela okucacile ukuthi ngabe i-CSB ibhekwa njengento yokulutha noma cha. Ucwaningo olwengeziwe luyadingeka ukuqonda ukuthi izici ze-neurobiological zihlobene kanjani nezinyathelo ezifanele emitholampilo ezifana nemiphumela yokwelapha ye-CSB. Ukuhlukanisa i-CSB njengendlela yokulutha ukuziphatha okuyoba nemiphumela ebalulekile emigomeni, imizamo yokuvimbela nokwelapha; Kodwa-ke, ngalesi sikhathi, ucwaningo lusencane. Njengoba kunikezwe ukufana okufanayo phakathi kwe-CSB kanye nezidakamizwa ezidakamizwa, ukungenelela okuphumelelayo kwezidakamizwa kungabamba isithembiso se-CSB, ngaleyo ndlela kuhlinzeke ukuqondisisa ngezinkombandlela zokucwaninga zesikhathi esizayo ukuphenya ngalokhu kungenzeka ngqo.
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