Izimvo: Olunye lophononongo oluninzi oluchaza ukuba umlutha ubangelwa ziinkqubo eziqhelekileyo, ezinjengokufunda kakhulu. Oku kukhomba-ku-1) zonke iziyobisi ezibandakanya iindlela ezifanayo, kunye ne-2) iziyobisi azibangelwa ziziphumo eziyityhefu zamachiza.
Neurobiol Funda Mem. 2011 Nov;96(4):609-23.
Torregrossa MM, Corlett PR, Taylor JR.
imvelaphi
ISebe lezeengqondo, Yale University School of Medicine, New Haven, CT 06508, USA.
Abstract
Kwiminyaka emininzi edlulileyo, ukukhotyokiswa kweziyobisi kuye kwamkelwa ngakumbi ukuba sisifo sobuchopho ngokuchaseneyo nokuba kungenxa yokunqongophala kwamandla okanye isiphene sobuntu. Ukuvezwa kwezinto ezikhobokisayo kubonakaliswe ukudala utshintsho oluhlala luhleli kulwakhiwo lobuchopho kunye nomsebenzi ekucingelwa ukuba ukhokelela ekuguqukeleni ekubeni likhoboka. Imiba ethile yofuzo kunye nokuba sesichengeni kokusingqongileyo ikwachaphazela impembelelo yeziyobisi zokusetyenziswa kakubi kwengqondo kwaye inokunyusa amathuba okuba likhoboka.
Utshintsho oluhlala ixesha elide ekusebenzeni kwengqondo lufunyenwe kwiisekethe ze-neural ezaziwa ngokuba luxanduva lokufunda okuqhelekileyo kunye neenkqubo zememori. kwaye kucingelwa ukuba iziyobisi zokusetyenziswa gadalala ziphucula ukufunda okuhle kunye nenkumbulo malunga nechiza ngelixa zithintela ukufunda ngeziphumo ezibi zokusetyenziswa kweziyobisi.
Ke ngoko, indlela yokuziphatha yekhoboka iya ngokuya ijolise ekufumaneni nasekusebenziseni iziyobisi zokuxhatshazwa, ngelixa kwangaxeshanye iphuhlisa isakhono esibuthathaka sokuyeka ukusebenzisa, nokuba iyeza lingenamvuzo kangako okanye liphazamisana nokusebenza kwezinye iinkalo zobomi. Kolu phononongo siza kuxoxa ngobungqina bekliniki bokuba abantu abakhobokileyo batshintshile ukufunda kunye nenkumbulo kwaye bachaze ii-neural substrates ezinokwenzeka zolu kungasebenzi. Ukongeza, siya kuhlola i-pre-clinical eubungqina bokuba iziyobisi zokusetyenziswa kakubi zibangela ukuphazamiseka okuqhubekayo kokufunda kunye nokukhumbula, Ukuphonononga utshintsho lweemolekyuli kunye ne-neurobiological olunokuthi lube sisiseko solu kuphazamiseka, misela imfuzo kunye nezinto ezisingqongileyo ezinokonyusa ukuba sesichengeni sokukhobokisa, kwaye ucebise ngezicwangciso ezinokubakho zokunyanga umlutha ngokusebenzisa ubuqhetseba bokufunda kunye nenkumbulo.
Ilungelo lokushicilela X XUMUM Elsevier Inc.
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