Qhagamshela kufundo lwantlandlolo- "I-Neural Correlates ye-Reac Reactivity Reactivity kuBantu ngabanye kunye nangaphandle kokunyanzeliswa ngokwesondo" (2014)
Qaphela - amanye amaphepha ahlaziywe ngoontanga ayavuma ukuba uSteele et al., 2013 ixhasa imodeli yokulutha kweziyobisi: Iingcaphephe ezihlaziyiweyo zontanga Steele et al., 2013
Inkcazo yokugxeka Steele et al., 2013 (c25 Steele et al.)
Iziphumo zethu zibonisa ukuba umsebenzi we-DACC ubonisa indima yesifiso sesini, esinokufana nokufunda kwi-P300 kwizifundo ze-CSB ezihambelanayo nomnqweno [25]. Sibonisa ukungafani phakathi kweqela le-CSB kunye namavolontiya anempilo ngelixa isifundo sangaphambili asizange sibe neqela lolawulo. Ukuthelekiswa kwesi sifundo samanje kunye neempapasho zangaphambili kwi-CSB egxile kwi-MRI ye-diffusion kunye ne-P300 kunzima kunikwa ukuhluka kweendlela. Izifundo ze-P300, isakhono esinxulumene nesiganeko esisetyenziselwa ukutyikitya ingqalelo kwiingxaki zokusetyenziswa kwezidakamizwa, bonisa amanyathelo aphezulu malunga nokusetyenziswa kwe-nicotine [54], utywala [55], kunye neopiates [56], ngamanyathelo aqhelekileyo ahambelana namaqhinga anqwenelayo. I-P300 iphinda isetyenziswe ngokusetyenziswa kwezidakamizwa zokusetyenziswa kwezidakamizwa kusetyenziswa imisebenzi engaqhelekanga apho iithagethi ezincinci zihlala zixutywe kunye neentlobo ezingenakucinga. Uhlalutyo lwe-meta lubonise ukuba izifundo ezixhatshazwayo ngeziyobisi kunye namalungu entsapho angenakuchaphazeleka ziye zanciphisa ubukhulu beP300 xa kuthelekiswa namavolontiya anempilo [57]. Ezi ziphumo zibonisa ukuba ukuphazamiseka kokusetyenziswa kweziyobisi kunokubonakaliswa kukungabikho kolwabiwo lwezixhobo zokuqwalaselwa kulwazi olufanelekileyo lomsebenzi (ekujoliswe kuko okungekho kweziyobisi) ngokunyusa ingqalelo yokujonga iziyobisi. Ukwehla kwe-P300 amplitude nako kunokuba sisiphawuli se-endophenotypic sokuphazamiseka ekusebenziseni iziyobisi. Izifundo ezinokubakho ezinxulumene nomsitho kugxilwe ekukhuthazeni ukubaluleka kwecocaine kunye ne-heroin cues eqhubeka inika ingxelo yokungaqhelekanga kwizinto ezisemva kwexesha le-ERP (> 300 milliseconds; [58]-[60]. I-LPP ikholelwa ukuba ibonakalisa kokubanjwa kokuqala kwangoko (400 ukuya kwi-1000 msec) kunye nokuqhutyelwa phambili kokuqhutyelwa kwe-stimuli ebalulekileyo. Izifundo nge-cocaine yokusetyenziswa kwezifo ziye zaphakamisa amanyathelo aseLPP kwangaphambili xa kuthelekiswa namavolontiya anempilo acetyisa indima ekuqwalaselweni kwangoko kwenkqantosi yenkxalabo ekhuthazayo kunye neempendulo ezithintekayo kwiimpawu ezimnandi zemoya. Nangona kunjalo, amanyathelo okugqibela we-LPP awazange ahluke kakhulu kwala mavolontiya anempilo [61]. Izixhobo ze-P300 ezinxulumene nomcimbi weempendulo ezichaphazelekayo zikholelwa ukuba yi-cortex yepariet [62]. Ngaloo ndlela, umsebenzi womsebenzi we-DACC kwi-CSB yophando kunye nomsebenzi we-P300 ochazwe kwisifundo sangaphambili se-CSB unokubonakalisa iinkqubo ezifanayo zenkqubo yokubanjwa kwenkcazo. Ngokufanayo, zombini izifundo zibonisa ukulungiswa phakathi kwezi nyathelo kunye nomnqweno ophuculweyo. Apha siphakamisa ukuba umsebenzi we-DACC uhambelana nomnqweno, ongabonakalisa inkcazo yokulangazelela, kodwa awuhambelani nokuthandabuza okuthandwayo kwindlela yokukhuthaza umlutha.
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