Ngaba i-dopamine receptors ingabonakalisa iingcinga malunga nokubheja?
I-Romeo iGigabha yeGigabha ibangela i-Baby Boom
Ihagu yeguinea ebizwa ngokuba yiSooty yonwabele ubusuku obunomdla kunye nabafazi abangamashumi amabini anesine emva kokukhohlisa indlela yabo eya kwikheji yabo emazantsi eWales. U-Sooty wanyanzela iihagu zaseguinea, nganye nganye, kwaye ngoku ungutata onekratshi weehagu ezingamawaka amane anesibini. . . . Waphazamiseka ngokupheleleyo. Sambuyisela ehokweni yakhe walala iintsuku ezimbini. ”
The Impembelelo yeCoolidge Isisombululo esomeleleyo sebhayoloji sokushiya iqabane lenoveli lingaqinisekiswanga nokuba kungakanani na iindleko. Kuqhelekile kwizilwanyana ezanyisayo, kuye kwabonwa nakwabasetyhini, kwaye kunokulandelwa yonke indlela ebuyela kuthi izalamane ezikude: iindonga. Nangona thina abantu bayabakhonkco ababini, inkqubo yethu yokubambisana iqhubana nalo mdala unethuba-luza kwenzeka ukucinga.
Zonke izenzo zezilwanyana, kubandakanywa ne-Coolidge Impact, zisekelwe ekunyuseni nasekuwa kweekhemikhali ze-neurokchemicals kunye noshintsho kwi-receptors. Uphando olutsha icebisa ukuba oomatshini abathile abasebenza ngasemva kobugorha bukaSooty banokuzilalela kwi-striatum-iqela elinzima lezinto ezisebenza njengendawo engumbindi wesekethe yomvuzo wobuchopho. I-striatum inxulunyaniswa nomvuzo kunye nokuchasa, kwaye inefuthe elinamandla kwizigqibo zethu. Ukwabelana ngesondo, uthando kunye nokudibana kuqhuba kwezi zakhiwo. Ukuba abakhanyisi, "ayenzeki."
Umzekelo, iziyobisi zokuzonwabisa zihlala zikhukula ingqondo nge-dopamine. Ii-neurons eziphambili kwi-striatum zisabela ngokucima amaqashiso e-D2 (dopamine) receptors, ezisa phezulu esiphelweni. Oku kuguqula iimvakalelo zomvuzo kunye nenkuthazo ide ingqondo ichache. Zimbalwa ii-receptors ze-D2 kubonakala ngathi zithetha ukuba, "Ndifuna i-dopamine ngakumbi ukuze ndizive ndilungile." Isekethe yomvuzo iyakhala ngenxa yovuselelo kwaye kuphela kwezinto ezinomdla ngokwenene eziya kwenza. Isini, iziyobisi kunye nerock 'n' roll ... okanye mhlawumbi Häagen Dazs. Ngapha koko, abasebenzisi beziyobisi abanzima abanee-dopamine receptors ezigqityiweyo bathambekele ekuphulukaneni nomdla kwezokwabelana ngesondo kunye nokudibana; badinga ukukhaba okungamandla. Ii-receptors ze-D2 zikwanceda ukubeka iziqhoboshi ekusebenziseni kakhulu. Zimbalwa ii-receptors ze-D2 ukwenza izifiso ezinzima ukuchasa.
Kuphando olukhankanywe ngasentla, izazinzulu ezifuna ukufunda ngakumbi malunga nokutya okudliwayo kubantu zichaze ezinye zeziphumo zokufumana i-dopamine-reception findings. Ukutya amaqanda okuvuselela ukutya (i-fat cheesecake kunye ne-sausage) ngokukhawuleza iyancipha inani labalamkeli be-D2. Phi? Kwi-striatum. Emva kokuba iifos zidle isitya sazo sokugqibela se-super-yummy, ukutya kwe-receptor kwahlala kuphantsi ubuncinane ubuncinane iiveki ezimbini (ubude bovavanyo).
Njengoko kunye nokusetyenziswa kweziyobisi zokuzonwabisa, i-striatum yasabela ekukhuliseni, kodwa yenza ngendlela eyahlukileyo kwindlela esabela kuyo, ithi, i-cocaine. Kwimeko ye-cocaine, ubuninzi be-D2 receptor bounces back back in two days (nangona ezinye iinguqu zinokuqhubeka). Kodwa ngokutya-a endalo i-reinforcer (i-buzz) -ukuncipha kwe-D2 kuyaqhubeka ixesha elide. Kuyathakazelisa ukuba ukupheliswa kuhlala ixesha elide emva kokutya, kuthathelwa ingqalelo ukuba icocaine ibangela ukuqhuma okukhulu kwe-dopamine. Ngaba inkqubo yemfuza iyakhaba?
Enye into eyingozi yayisenzeka, nayo. Njengokuba kunjalo nokusetyenziswa kweziyobisi, ubuchopho beerandi babhalisiwe mnandi ukwenziwa kusebenze. Kwaye kubonisiwe kwindlela abaziphethe ngayo emva kokutya kakhulu: i-rat chow esemgangathweni ilahlekelwe sisibheno. Ukusetyenziswa kuhlala kusezantsi kunesiqhelo kwiiveki. "I-Cheesecake okanye akukho nto," iigundane zibonakala ngathi ziyacinga. (Okubangela umdla kukuba, iiopioid eziveliswa kukusetyenziswa kweswekile zisebenza njenge enye indlela yokuchasana ngokuphazamisa ukukhiqizwa kwe-oxytocin.)
Ngokucacileyo, "i-binge trigger" (ngokusebenzisa nayiphi na indlela) sisixhobo sokuzivelela kwimeko apho ukusinda kuqhubeka ngokuziphatha. idlulile kwinqanaba lokuhlala ngokuqhelekileyo. Cinga ngebhere egreyid kwi-salmon enamafutha aphezulu ngaphambi kokulala. Okanye iingcuka, ezifuna ukubala ziye kuthi ga kwiiponti ezingamashumi amabini zokubulala kube kanye. Okanye ookhokho bethu, ababefuna ukugcina iikhalori ezikumgangatho ophezulu njengeeponti ezimbalwa ezongezelelweyo zothutho olulula ukuze siphile kumaxesha anzima. Okanye wena xa uxinene ne-turkey kunye neetapile ezicujiweyo kunye nepayi yakho oyithandayo yokubulela iyavela.
Xa ubuchopho bethu bokuqala bubona into ethile luleke kakhulu, ifuna ukuba sisebenzise eli thuba libalaseleyo… ngokupheleleyo. Ayinakukwenza oko ngeemvakalelo ezifudumeleyo, ezothusayo zokwoneliseka. Hayi. Kuya kufuneka yenze iimvakalelo ze ukuswela or ukunganeliseki (iiminqweno) ukuze sikwazi ukuqhubela phambili kwimida yethu eqhelekileyo.
Utshintsho oluphambili kwii-receptors lusenza sizive ngathi into… ayilunganga. Sifuna ukuziva kamnandi kwakhona, nokuba kuthatha ntoni. Ayizizo zonke izinto eziza kuyenzela thina, nazo. Asiyi kuhlala eqhelekileyo, kuba iingqondo zethu zifuna ukuba sigxile kwizinto ezintle… kuphela. Amanqanaba aqhelekileyo edopamine awanelanga. Siya kuba nzima. Sifuna into ethe kratya, into ebhalisa "njengexabiso eliphezulu" (nokuba ayisiyiyo), into eya kubangela ukukhutshwa kwe-dopamine (kunye nokuphendula kolonwabo) ingqondo yethu ngoku inqwenela. I-Dopamine ikhutshwa xa into ibhetele kunokuba bekulindelwe, kwaye i-spike ye-dopamine iya kuvuselela ii-receptors ezimbalwa eziseleyo kwi-striatum ukusinika enye incasa yeemvakalelo ezilungileyo… ngaphambi kokuba siziva singonelisekanga kwakhona.
Gcina ukhumbula ukuba umvuzo womsebenzi wesekethe kukuhlala ungonelisekanga kancinci naphantsi kwezona meko zibalaseleyo. Ngale ndlela, sikhuthazekile ukuba sibambe amathuba athembisayo, okanye sijonge phambili ngentumekelelo kulwaneliseko olumiselweyo lwempumelelo, ukuthandana ngempumelelo okanye ukonga ukonyusa ukhetho lwexesha elizayo.
Ngokwesiqhelo eli cala lokwenziwa kwethu lisinika umdla wobomi kunye nokufezekisa. Kodwa xa sigqithisa ukukhuthaza kwaye sinqwenela ukungabikho komvuzo kwisekethe yethu, iziyolo eziqhelekileyo kunye nezicwangciso zamabhongo ngekamva aziboneleli nge-buzz eqhelekileyo. Okubi nangakumbi kukuba, asinakukuxabisa ubudlelwane kunye nothando olufudumeleyo esizalwa nalo, iimanyene ezibophelelayo ezidinga imo yempilo. Endaweni yoko, sinokuziva singonelisekanga-nditsho nabantu esibathandayo- kwaye siqinisekile ukuba nasiphi na isiphoso sikubo ngokungazifezekisi iimfuno zethu ezibaxiweyo. Sifuna ukwaneliseka kwangoko, nokuba sibeka engozini iinjongo zethu zekamva. Imfuza yethu iye yathimba ingqalelo yethu ngempumelelo zabo injongo.
Ngaba ukuqonda okungcono kwindlela ukuvuselela kakhulu ukuguqula i-receptor ukuxininisa kunceda abantu ukuba baqonde ukuba i-65% yamaMerika ibininzi kakhulu kwaye amadoda anakho iikhompyutha yonke indawo ayifumana i-intanethi ye-porn riveting? Ngaba sinyanzeliswa ngama-receptors aphantsi we-D2 kunye nezinye iinguqu zengqondo ezibangelwa yiyo, yayiza kuba yintoni okhokho bethu, ukuvuselela ngokwenene?
Cinga ngoSooty ethatha ithuba lakhe kwinkundla yabafazi bakhe. Okanye imvumi uvumo lukaJohn Mayer ukuba ngoku ukhetha iiyure zoononophelo kubudlelwane nabafazi bokwenyani. (Ewe ewe, abasetyhini bazinkcinkca ngotywala khekhe nabo. Bona (imvumi) 'UKaty Perry weqa ukusebenza ukuze abukele iphonografi!')
Isibonakaliso sengqondo sobuchopho sibe yimbopheleleko enobungozi apho ukutya okunokubaluleka kakhulu okanye amaqabane avuselelekayo athile atholakalayo uncedo olungapheliyo. Xa i-binge trigger ihlala isebenza, ulwaneliseko luyasishiya ngaphandle kokutya esikutyayo okanye esikufumanayo. Ngelishwa, xa umntu ezifumanisa efuna ishushu kwaye eshushu ngakumbi, ayisiyiyo kuba ufumana ulonwabo ngakumbi, kodwa ngenxa yokuba efumana Ngaphantsi. Umphefumlo womoya uzukile kumfazi orhaxwayo kuba ioksijini yakhe iphantsi. Kwangokunjalo nengqondo ebindindisholo ifuna into engenayo- ukuvuselela okumnandi- kuba uvakalelo lwayo oluqhelekileyo luyancitshiswa. Umnqweno onamandla wokufuna uyolo unokuphazama ngokulula njengokonwaba, nokuba kunzima ukuwenza thembiso yolonwabo.
Iigundane ezikwisifundo zakhawuleza zityebe xa zinikwa inani elingenamda lezinto ezingaphezulu. Ngokungafaniyo neempuku eziqhelekileyo, khange babeke zinto zilungileyo naxa besoyikiswa ngumbane. Badla ngokutya okugqithisileyo okungenampilo; abonelisekanga. Cinga ngamakhoboka eziyobisi.
Ngaba abasebenzisi be-porn bayasokola nxamnye nale nto inokubangela ukuba bangene kwi-striatum xa bengenakufumana ngokwaneleyo "amaqabane" amatsha axhokonxayo abecofa kunqakrazo ngalunye? I-Sooty yafumana ukuphumla okufuneka kakhulu emva kokudibana kunye nekheji egcwele abafazi, kodwa umsebenzi womntu ongamanyala ze yenziwe. Kuhlala kukho elinye "iqabane" elililo lokuncwina. Iingqondo zethu zisikhokelela ekubeni sihlale emsebenzini xa izinto ezintle zisanda. Kubonakala ngathi kukho into eyahlukileyo ngokuphendula kwengqondo yethu kukutya okulingayo kunye nokuvuselelwa ngokwesondo.
Kusenokwenzeka ukuba xa i-orgasm ingakhange inike uluhlu olupheleleyo lokuthomalalisa ziphatha (njengoba ngesondo ngaphandle komlingane), sesichengeni ngokukhethekileyo ukuba sizive singonelisekanga kungekudala emva koko. Emva kwayo yonke loo nto, ngokwembono yethu yemfuza, uxanduva lwethu lokuchumisa alwenziwa. Ukuba kunjalo, ngaba olu phondo luyinyani libido-okanye ukungoneliseki okwenziweyo okubangelwa lutshintsho lobuchopho oluthomalalisa iimvakalelo zolwaneliseko?
Ngaba kunokwenzeka ukuba nokuba yenye ye-orgasm ngamanye amaxesha inyuse iminqweno elandelayo? Akukho mntu uyazi ngokuqinisekileyo. Nangona kunjalo, i-rat's dopamine receptor density iye yehle kabukhali ngoncedo lwayo lwasezulwini lokutya okunamafutha. Kubonakala ngathi kukho ukugqabhuka kwesiqalo sokuzinkcinkca okuqhuba ngokudibana kunye nokutya. Ukufumana kwakhona abasebenzisi be-porn bafumanisa ukuba ukutya ukutya okungafunekiyo kuyonyusa iminqweno ye-porn ngexesha lokurhoxa. Kwaye mhlawumbi ulivile ihlaya elidumileyo malunga nentombi efanelekileyo, ejika ibe yi-pizza ezinzulwini zobusuku.
I-neurochemistry ye-orgasm kunye nokutya ngokuqinisekileyo akunakuncitshiswa kutshintsho lwe-D2-receptor. Nangona kunjalo, utshintsho lwe-receptor ngokuqinisekileyo lunokuba yinxalenye yephazili lokuba kutheni ngamanye amaxesha umnqweno wesini ukhula ngaphandle kokubonelela ngokwaneliseka. (Ukuba umxholo wokulibala umjikelezo emva kwe-orgasm elitsha kuwe, unokuba unomdla wokufunda ukuba uphando sele luveze umjikelezo ubuncinci iintsuku ezisixhenxe kumadoda.)
Mhlawumbi uphando luya kuthi ngenye imini lubonelele ngemephu yendlela yotshintsho lobuchopho emva kwezenzo ezahlukeneyo zesondo. Emva koko asiyi kushiywa kuphela kwinceba ye-binge yethu ebangela ukuba sikhangele ulwaneliseko.
Uhlaziyo:
- 2019 - Kwiimpuku, ukutya okunamafutha aphezulu kusika 'i-brake' esetyenziselwa ukulawula ukuthanda ukutya
- 2016 - Abaphengululi bavula iinkqubo kwiingqondo ezahlula ukusetyenziswa kokutya kwiinqwenela
- 2015 - I-Dopamine Surge May Ingachaza Ukutya Kwakho: I-Insulini Eboniswe Ukusebenza Iimpawu Zomvuzo KwiBrain Yakho
- Ngo-2010-Izibalo zaMazwe aMnandi kwilizwe
Oku ngakumbi malunga nophando oluphambili:
Ecacisiwe umphandi uPaul Kenny, ingqondo ikhupha i-dopamine ekuphenduleni kumava amnandi njengokutya i-cheesecake, ukulala ngesondo okanye ukucofa i-cocaine. Kodwa, ulonwabo oluninzi luthintela indlela yomvuzo wobuchopho ngokugqitha kwi-D2 receptor kwaye ibangele ukuba icime. Kwiigundane ezikhobokiswe kukutya okungekho mpilweni, ekuphela kwendlela yokukhuthaza amaziko abo okonwaba yayikukutya ukutya okunamafutha aphezulu, ukutya okunekhalori ezininzi. "Abanawo umvuzo ngendlela ebekufanele ukuba bayenze," utshilo uKenny.
ENTSHA: Kutheni kunzima ukutya? (Uphando lweTufts luqinisekisa ukuba "izilwanyana ezityebileyo nezityebileyo zombini" zinesiphene ngokufanayo kwingqondo-ukunqongophala okubonakalayo kwedopamine ekhutshwe kwisiza esidibanisa umvuzo. "
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