MAFUNSO: Zotsatirazi zimachokera ku zokambirana zachinsinsi zomwe zimagwira ntchito. Wolemba ndi pulofesa wa biology yobereka.
Pali maphunziro osachepera awiri omwe adapeza kuti amuna omwe ali ndi hypogonadal amatenga zovuta mosavuta monga momwe amachitira amuna omwe ali ndimagulu amtundu wa T akamakumana ndi zovuta zogonana. Utsogoleri wa T sunawonjezere zovuta. Kusiyanitsa kokha pakati pa amuna ndi ma hypogonadal ndikuwongolera ndikuti amuna a hypogonadal amasungabe zomwe adachita kwakanthawi kuposa kuwongolera. Komabe, amuna a HG amayenera kukumana ndi zoyipa zakugonana kuti apeze zovuta.
Kusiyanitsa kwakukulu pakati pa amuna ndi ma hypogonadal ndikuwongolera ndikuti amuna a HG samangosonyeza zokha ndipo samakhala ndi zovuta zakumadzulo.
Potero popanda T kulimbikitsanso kukakamizidwa, koma amuna amatha kukhala ndi zovuta zowonongeka.
Nazi zizindikiro ziwiri za maphunziro aumunthu:
- 1983. Chikhalidwe Cha Androgen Kuchita Zokhudza Kugonana Kwa Amuna Ndi Akazi - Kafukufuku Wophatikiza-Wodzilemba Wokha pa Amayi a Hypogonadal.
- 1984. Thandizo la Testosterone Kwa Kugonana Kwambiri Ndi Erectile Kusayenerera Mwa Amuna: Phunziro Lolamulidwa.
Bagatell awonetsa kuti kupondereza wamwamuna T wokhala ndi GnRH analogue kumachepetsa kwambiri chilakolako chogonana, komanso kuseweretsa maliseche. Zotsatira za T mwa amuna pakusintha molimbika zikuwonekeratu. Sizikuwoneka kuti pali vuto lililonse pamtundu wa amuna kuti athe kupeza erection potengera kukondoweza. Mwa njira, tidapeza zomwezi mwa anyani omwe ma androgens adatsitsidwa ndi analogue a GnRH. Kulimbikitsana kukwatiwa kunachepetsedwa. Ngati wamwamuna ali ndi udindo wapamwamba amapitilizabe kukwera (anyani achikazi amayambitsa kugonana m'magulu athu kotero kuti kugonana sikudalira zofuna zamwamuna), koma amuna otsikawo adayimilira ponseponse kuwonetsa kuti amafunikira chilimbikitso chokwatirana kuti athane ndi wamwamuna- mpikisano wamwamuna mgululi. Phoenix adanenanso zaka zapitazo kuti anyani amphongo omwe adatenthedwa kwa zaka zopitilira 5 adasunthidwabe chifukwa chokhala ndi mkazi womvera ndipo pafupifupi 25% ya iwo amapitabe kukwatirana ndikuwonetsa malingaliro okomoka.
Nayi gawo la Bagatell. 1994. Zotsatira za testosterone yodalirika ndi estradiol pa khalidwe la kugonana mwa anyamata achichepere.
Ndipo nyani wathu 1991. Wotsutsa (Nal-Lys GnRH wotsutsa) kuthetsa ntchito ya pituitary-testicular ndi khalidwe la chiwerewere m'magulu a rhesus monkeys.
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