Kufufuza kwa ubongo kumawunikira miyeso ya zokopa za chokoleti: Enkephalins amayamba kudya (2012)

September 20th, 2012 mu kufufuza kwachipatala

Ma enkephalin a extracellular anakula pomwe makoswe adayamba kudya chokoleti cha mkaka M & Ms. Kuyamba kudya kunagwirizana ndi kuwonjezeka kwamphamvu kwa ma enkephalin owonjezera (met and leu), omwe adakhalabe olimba pakudya ndipo pang'onopang'ono adayamba kudya. Kukula kwa enkephalin kumawonjezeka mwa anthu omwe amalumikizana ndi kuchedwa kwawo kudya M & M yawo yoyamba: kuchuluka kwa enkephalin kwa omwe amadya mwachangu kwambiri.

Ndalama: Tsopano Biology, DOI: 10.1016 / j.cub. 2012.08.014

Ochita kafukufuku ali ndi umboni watsopano mu makoswe kuti afotokoze momwe zilili kuti chokoleti chokoleti chingakhale chosatsutsika kwathunthu. Chilakolako chodyera zakudya zokoma ndi zonunkhira bwino kwambiri zimaphatikizapo mbali yosayembekezereka ya ubongo ndi kupanga zachilengedwe, monga opium-like chemical, malinga ndi lipoti lofalitsidwa pa Intaneti pa September 20th mu Current Biology. 

"Izi zikutanthauza kuti ubongo umakhala ndi machitidwe ochulukirapo omwe amapangitsa anthu kufuna kuwonjezerapo mphotho kuposa momwe amalingalira kale," atero a Alexandra DiFeliceantonio aku University of Michigan, Ann Arbor. "Pakhoza kukhala chifukwa chimodzi chomwe kuchuluka kwa mowa kwambiri kuli vuto masiku ano."

Gulu la a DiFeliceantonio lidazindikira izi popatsa makoswe mphamvu yolimbikitsira ndi mankhwala omwe amaperekedwa molunjika kudera laubongo lotchedwa neostriatum. Nyamazo zinadzikhutitsa ndi kuwirikiza kawiri kuchuluka kwa chokoleti cha M & M kuposa momwe akadadya. Ofufuzawo apezanso kuti enkephalin, mankhwala achilengedwe onga mankhwala omwe amapangidwa m'dera lomwelo laubongo, adakulira pomwe makoswe adayamba kudya timiyala tomwe timakutidwa ndi maswiti.

Sikuti enkephalins kapena mankhwala ofananawo amapangitsa makoswe kukhala ngati chokoleti kwambiri, ofufuzawo atero, koma kuti mankhwala amubongo amakulitse chilakolako chawo ndikulakalaka kuwadya.

Zomwe apezazi zikuwonetsa kuwonjezeka modabwitsa kwa gawo la neostriatum, monga DiFeliceantonio amanenera kuti dera laubongo limalumikizidwa makamaka ndi kuyenda. Ndipo pali chifukwa choyembekezera kuti zomwe zapezeka mu makoswe zitha kutiuza zambiri zakomwe timakonda kudya.

"Malo amomwe timayeserera pano amagwiranso ntchito anthu onenepa kwambiri akawona zakudya komanso pomwe anthu omwe ali ndi vuto lomwetsa mankhwala osokoneza bongo akuwona zochitika zamankhwala osokoneza bongo," akutero. "Zikuwoneka kuti zomwe tapeza mu enkephalin mu makoswe zimatanthauza kuti neurotransmitter iyi imatha kuyambitsa mitundu yambiri ya kudya mopitirira muyeso komanso chizolowezi mwa anthu."

Ofufuza tsopano akuyembekeza kufotokozera zochitika zina zomwe ena angafune kuti titha kuchita zambiri: zomwe zimachitika mu ubongo wathu pamene tikudutsa pafupi ndi malo ogulitsira zakudya omwe timakonda kwambiri ndikuwona kuti mwadzidzidzi tifuna kusiya.

Zambiri: DiFeliceantonio et al.: "Enkephalin akukwera mu dorsal neostriatum ngati chizindikiro chodya." CHITANI: 10.1016 / j.cub.2012.08.014

"Kuphunzira zaubongo kumavumbula zoyambitsa zokopa chokoleti." Seputembala 20, 2012. http://medicalxpress.com/news/2012-09-brain-reveals-roots-chocolate-temptations.html

Enkephalin akukwera m'mwamba mwa nositriatum ngati chizindikiro chodya.

Biology Yamakono, 20 September 2012
Copyright © 2012 Elsevier Ltd Malamulo onse ndi osungidwa.
10.1016 / j.cub.2012.08.014

olemba

 
Mfundo
  • Enkephalin akukwera mu neostriatum amayamba chifukwa chodya mphoto zabwino
  • Kudya kwambiri kumapangidwira mwachindunji ndi mbali imodzi yothana ndi neostriatum
  • Kulimbikitsa kotchedwa Neostriatum opioid kumayambitsa kudya koma osati "kukonda" kukoma

Chidule

Kugonjetsedwa kwakukulu kwa mphotho kumayambitsa matenda omwe amayamba chifukwa chodya mowa mwauchidakwa. Pano, timapereka umboni wakuti enkephalin ikugwiritsidwa ntchito m'chaka chotsatira cha mankhwala osokoneza bongo amachititsa kuti chakudya chikhale chokoma kwambiri. Mu ventral striatum, m'mayendedwe a opioid amapereka chigawo chofunikira cholimbikitsira kudya mphotho [1,2,3,4]. M'malo osokoneza bongo, m'mapangidwe a opioid amalowetsa m'magulu amtunduwu omwe amalandira ziphuphu zochokera kumalo a ziwalo za prefrontal cortex [5,6,7,8,9,10,11,12,13]. Tidagwiritsa ntchito njira zapamwamba za opioid microdialysis zomwe zimaloleza kuzindikira kuchuluka kwa ma enkephalin akunja. Endogenous> 150% enkephalin surges in anterior dorsomedial neostriatum adayambitsidwa pomwe makoswe adayamba kumwa chokoleti chokoma. Mosiyana ndi izi, magawo a dynorphin sanasinthe. Kuphatikiza apo, gawo lomwe limayambitsa kukondoweza kwa opioid pakuchulukitsa kunawonetsedwa ndikuwona kuti microinjection munthawi yomweyo ya dorsomedial quadrant ya mu receptor agonist ([D-Ala2, N-MePhe4, Gly-ol] -enkephalin; DAMGO) yatulutsa kwambiri> Kuwonjezeka kwa 250% pakudya chakudya chotsekemera chokoma (osasintha kusintha kwa zonunkhira za hedonic). Kujambula ndi njira za "Fos plume" zatsimikizira tiye amawoneka kuti amatha kudziwika kuti ali ndi malo omwe amachititsa kuti asamayende bwino, koma ena omwe sanagwire ntchito. Zofukufukuzi zimasonyeza kuti zizindikiro za opioid mu anteromedial dorsal neostriatum zimatha kulembetsa komanso zimapangitsa kuti azidya mphoto.