Tanthauzirani Psychiatry. 2017 Apr 4; 7 (4): e1085. doi: 10.1038 / tp.2017.55.
Fujimoto A1,2, Tsurumi K1, Kawada R1, Murao T1, Takeuchi H1, Murai T1, Takahashi H1,2.
Kudalirika
Matenda a juga (GD) nthawi zambiri amawonedwa ngati vuto lokonda kukhala pachiwopsezo. Komabe, zizindikilo za GD sizingamvetsetsedwe ndi mawonekedwe awa. Pakafukufuku waposachedwa, tidayesa kuti odwala a GD nawonso anali ndi vuto lakuwongolera mayendedwe pangozi (kutengera njira zodalira boma), ndipo cholinga chake chinali kufufuza njira zomwe zimayambitsa kutenga chiopsezo cha GD. Pofuna kuthana ndi vutoli, tinayesa odwala a GD opanda comorbidity (GD group: n = 21) komanso otenga nawo mbali pazoyang'anira zaka (HC gulu: n = 29) pantchito yanjuga yazambiri, momwe ophunzira amafunikira kuchotsa 'block quota '(ofunikira mayunitsi kuti athetse bwalo, ma 1000-7000 mayunitsi) pazisankho 20, ndikuchita kuyeserera kwa maginito (fMRI) yogwira ntchito. Kusanthula kwamakhalidwe kunavumbulutsadi kusintha kosasintha kwa malingaliro pagulu la GD; Gulu la GD linalephera kupewa kusankha koopsa pamtundu wina wa masanjidwe (otsika kwambiri), momwe njira zowopsa sizinali zotheka kuthetsa vutolo. Chifukwa chake, kuwunika kwa fMRI kunawonetsa kuchepa kwa magwiridwe antchito a dorsolateral pre mbeleal cortex (dlPFC), yomwe yakhudzidwa kwambiri pakusintha kwazidziwitso. Pazidziwitso zathu, kafukufuku wapano adapereka umboni woyamba wopatsa mphamvu pakukweza njira zodalira boma mu GD. Kuyang'ana pakuwongolera kosintha kwa chiopsezo pamagawo angapo kumathandizira kuti mumvetsetse bwino za psychopathology ya GDs.
PMID: 28375207
PMCID: PMC5416696
DOI: 10.1038 / tp.2017.55
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