Neuropsychopharmacology. 2016 May 6. onetsani: 10.1038 / npp.2016.68.
Rigoli F1, Rutledge RB1,2, Kutafuna B1, Ousdal OT1,3, Dayan P4, Dolan RJ1,2.
Kudalirika
Ngakhale kukhudzika kwa dopamine pakuphunzira kwamalipiro kwalembedwa bwino, momwe zimakhudzira mbali zina zamakhalidwe zimakhalabe mutu wa ntchito zambiri. Mankhwala a Dopaminergic amadziwika kuti amachulukitsa chiopsezo, koma njira zomwe zimapangitsa izi sizikudziwika. Tidasanthula gawo la dopamine pofufuza momwe zomwe zimayambitsidwira ndi L-DOPA pazosankha za anthu athanzi omwe ali nawo mu paradigm yoyesera yomwe idalola magawo ena pachiwopsezo kudziwika. Tikuwonetsa kuti machitidwe osankha amatengera gawo loyambira (mwachitsanzo, kudziyimira pawokha) kutchova juga, kukonda njuga kukulira ndi kuchuluka / kusiyanasiyana, komanso kufunika kwazomwe zimakhazikika. Kuchulukitsa milingo ya dopamine kunakulirakulira kungoyambira kokhazikika pamayendedwe amtundu wa njuga, kusiya zina zomwe sizinakhudzidwe. Zotsatira zathu zikuwonetsa kuti mphamvu ya dopamine pamakhalidwe osankhidwa imakhudza kusinthasintha kwakanthawi kosankha koopsa-kupeza komwe kumatanthauza kumvetsetsa ma psychopathologies okhudzana ndi mphotho kuphatikiza kusuta.
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