Kutulutsidwa kwa dopamine mu ventral striatum kwa otchova jekeseni a pathological akutaya ndalama. Linnet J, Peterson E, Doudet DJ, Gjedde A, Møller A. Acta Psychiatr Scand. 2010 Oct; 122 (4): 326-33. Center of Functionally Integrated Neuroscience, Aarhus University, Aarhus, Denmark. [imelo ndiotetezedwa]
Cholinga: Kufufuza za dopaminergic neurotransmission yokhudzana ndi mphotho zandalama komanso kulangidwa pamatenda am'magazi. Omwe amatchova njuga (PG) nthawi zambiri amapitiliza kutchova juga ngakhale atayika, omwe amadziwika kuti 'kuthamangitsa zomwe munthu wataya'.
Tidangoganiza kuti kutaya ndalama kungalumikizidwe ndi kutulutsidwa kwa dopamine mu ventral striatum ya PG poyerekeza ndi maulamuliro athanzi (HC).
NJIRA: Tidagwiritsa ntchito Positron Emission Tomography (PET) yokhala ndi [(11) C] raclopride kuyeza kumasulidwa kwa dopamine mu ventral striatum ya 16 PG ndi 15 HC kusewera Iowa Masewera a Paskha (IGT).
Zotsatira: PG yemwe adataya ndalama adakulitsa kwambiri kutulutsidwa kwa dopamine mu ventral striatum wamanzere kuyerekeza ndi HC. PG ndi HC omwe adapambana ndalama sizinali zosiyana pakumasulidwa kwa dopamine.
POMALIZA: Zomwe tapeza zikuwonetsa kuti ndalama zomwe zimatayika pamtundu wa njuga ndizomwe zingafotokozere za kuthamangitsa. Zomwe apezazi zingakhale ndi tanthauzo loti amvetsetse vuto la dopamine komanso kusankha kwaulere pamasewera a juga komanso zokhudzana ndi zosokoneza bongo.
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