Kulemera kwa cortical mu vuto la juga: a MRI study (2015)

Vuto lakutchova juga ladziwika kuti ndi "chizolowezi chamakhalidwe" chifukwa chophatikizidwa mgulu la DSM-5 la 'Zinthu Zokhudzana ndi Zinthu Zosokoneza bongo komanso Zowonjezera Zowonjezera.' Ngakhale adapeza kumene komanso kuchuluka kwa 1-3% padziko lonse lapansi, ndizochepa zomwe zimadziwika pokhudzana ndi neurobiology yamatendawa. Cholinga cha phunziroli chinali kuwunika ma cortical morphometry mu vuto losatchova juga, kwa nthawi yoyamba. Omwe ali ndi vuto la kutchova juga (N = 16) opanda mankhwala amakono a psychotropic kapena comorbidities amisala, ndikuwongolera athanzi (N = 17), adalowa nawo phunzirolo ndikuyamba kujambula kwa maginito (3T MRI). Makulidwe amtundu wa Cortical adafotokozedwa pogwiritsa ntchito njira zamagawo (FreeSurfer), ndipo kusiyana kwamagulu kunazindikirika pogwiritsa ntchito kusanthula kwa magulu amtundu wa permutation, ndikuwongolera mwamphamvu pakufananiza kambiri. Vuto lakutchova juga limalumikizidwa ndi kuchepa kwakukulu (pafupifupi 15.8-19.9%) pakulimba kwamphamvu, motsutsana ndi kuwongolera, makamaka m'magawo oyang'ana kutsogolo. Amatchulidwira molakwika kumaso kwamitsempha yamaubongo komwe kumachitika muvuto la kutchova juga, kuthandizira kufalikira kwamatenda okhudzana ndi zovuta zamankhwala komanso kusinthidwa kwawo posachedwa monga chizolowezi chamakhalidwe. Ntchito yamtsogolo iyenera kuwunika mikhalidwe motsutsana ndi zomwe zapezedwa komanso ngati kufanana kulipo ndi zina zomwe sizinakonzedwenso zosokoneza bongo.