Behav Ubongo Res. 2014 Sep 6. pii: S0166-4328 (14) 00576-2. doi: 10.1016 / j.bbr.2014.08.057
Meng YJ1, Deng W1, Wang HY2, Guo WJ3, Li T4.
Kudalirika
Kafukufuku waposachedwa wogwira ntchito ngati ma virus a resonance imaging (fMRI) apeza madera ambiri muubongo momwe kutchova juga kumathandizira kapena kupereka mphoto kwa ma activation ndipo kungawunikitse mikangano yomwe ikupitilira pokhudzana ndi kufotokozera komwe kumayambitsa matenda osokoneza bongo komanso matenda am'mimba. Komabe, palibe maphunziro mpaka pano omwe adasanthula mwatsatanetsatane maphunziro a fMRI a GD kuti athe kusanthula malo a ubongo omwe adakhazikitsidwa ndi machitidwe okhudzana ndi kutchova njuga ndikuwona ngati madera omwe adakhazikitsidwa mosiyana pakati pa milandu ndi kayendetsedwe kabwino (HC). Kafukufukuyu adawunikiranso zolemba za 62 zomwe adasankhazo ndipo pomaliza adasankha maphunziro a 13 omwe ali ndi nzeru zowunika za ubongo kuti achite zochulukirapo za kusanthula kwa meta pogwiritsa ntchito njira yolondola yosainira mapu. Poyerekeza ndi HC, odwala GD adawonetsa activation yayikulu ya lentiform minus ndikumanzere kwapakati pa occipital gyrus. Zochita zowonjezereka mu maukono a lentiform poyerekeza ndi HC zinapezekanso m'magulu onse a GD omwe anali, kapena sanatero, osagwiritsa ntchito mankhwala osokoneza bongo monga comorbidity. Kuphatikiza apo, ma Scores a South Oaks Guga Screen adalumikizidwa ndi hyperactivity mu lenti yolondola ya lentiform ndi ma parahippocampus apakati, koma molakwika zokhudzana ndi kutsogola kutsogolo kwa gyrus. Zotsatirazi zikuonetsa kusowa kwa njira ya kutsogolo kwa GD, zomwe zitha kutithandizira kumvetsetsa kwamagulu ndi tanthauzo la GD komanso kupereka umboni wakuyambiranso kwa GD ngati chizolowezi chochita mu DSM-5.
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