gwero
Department of Psychiatry, Chung Ang University, College of Medicine.
Kudalirika
Bupropion wagwiritsidwa ntchito pochiza odwala omwe amadalira mankhwala chifukwa cha kufooka kwake kwa dopamine ndi norepinephrine reuptake.
Tidawerengera kuti ma 6 masabata a bupropion okhazikika amasulidwe (SR) amachepetsa kulakalaka kusewera pa intaneti komanso kanema wa masewera olimbitsa thupi omwe adalimbikitsa bongo omwe ali ndi vuto la masewera a pa intaneti (IAG).
Mitu khumi ndi imodzi yomwe idakwaniritsa zofunikira za IAG, kusewera StarCraft (> 30 hr / sabata), ndi maphunziro asanu ndi atatu oyerekeza athanzi (HC) omwe anali ndi luso kusewera StarCraft (<masiku atatu / sabata ndi <3 hr / tsiku). Poyambira komanso kumapeto kwa milungu isanu ndi umodzi ya chithandizo cha bupropion SR, zochitika muubongo poyankha StarCraft chiwonetsero chazomwe adayesedwa pogwiritsa ntchito 1 Tesla functional MRI. Kuphatikiza apo, zisonyezo zakukhumudwa, kulakalaka kusewera masewerawa, komanso kuopsa kwa chizolowezi chogwiritsa ntchito intaneti adayesedwa ndi Beck Depression Inventory, kudzidziwitsa nokha zakulakalaka pamiyeso ya 6-point analogue scale, ndi Young's Internet Addiction Scale, motsatana.
Poyankha pamasewera a masewerawa, IAG idawonetsa kuyendetsa ubongo kwakumanzere kwa michere yanyumba, kumanzere kwanyumba yakumanzere, ndikusiya gitala ya parahippocampal kuposa HC.
Pambuyo pa sabata ya 6 sabata la bupropion SR, kukhumba masewera amasewera pa intaneti, masewera osewerera nthawi yonse, komanso kuchita kwa ubongo kudzera mu dorsolateral prefrontal cortex kumachepetsedwa mu IAG. Tikuwonetsa kuti bupropion SR ingasinthe zolakalaka ndi zochitika muubongo m'njira zofanana ndi zomwe zimawonedwa mwa anthu omwe amwa mankhwala osokoneza bongo kapena odalira.
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