Ulalo wa kafukufuku woyambirira - "Ma Neural Correlates a Sexual Cue Reactivity mwa Anthu Omwe Ali ndi ndi Opanda Makhalidwe Ogonana Okakamiza" (2014)
Zindikirani - mapepala ena ambiri owunikidwa ndi anzawo amavomereza kuti Steele et al., 2013 imathandizira chitsanzo cha chizolowezi chogonana: Ndemanga zowunikidwa ndi anzawo za Steele et al. , 2013
Kufotokozera momveka bwino Steele et al., 2013 (cXation ndi 25 Steele et al.)
Zomwe tapeza zikusonyeza kuti zochita za dACC zikuwonetsa ntchito ya chilakolako chogonana, chomwe chingafanane ndi kafukufuku wa P300 mwa anthu a CSB okhudzana ndi chilakolako [25] . Tikuwonetsa kusiyana pakati pa gulu la CSB ndi odzipereka athanzi pomwe kafukufuku wakaleyu analibe gulu lowongolera. Kuyerekeza kwa kafukufukuyu waposachedwa ndi zofalitsa zakale mu CSB zomwe zikuyang'ana pa MRI yofalikira ndi P300 n'kovuta chifukwa cha kusiyana kwa njira. Kafukufuku wa P300, kuthekera kokhudzana ndi zochitika komwe kumagwiritsidwa ntchito pophunzira tsankho la chidwi pamavuto ogwiritsa ntchito mankhwala osokoneza bongo, akuwonetsa miyeso yokwera pankhani yogwiritsa ntchito nikotini [54] , mowa [55] , ndi ma opiates [56] , ndi miyeso yomwe nthawi zambiri imagwirizana ndi zizindikiro zakulakalaka. P300 imaphunziridwanso nthawi zambiri m'mavuto ogwiritsa ntchito mankhwala osokoneza bongo pogwiritsa ntchito ntchito zachilendo momwe zolinga zochepa zothekera nthawi zambiri zimasakanizidwa ndi zinthu zomwe sizili zolinga zazikulu. Kusanthula kwa meta kunawonetsa kuti anthu omwe ali ndi vuto la kugwiritsa ntchito mankhwala osokoneza bongo ndi achibale awo omwe sanakhudzidwe adatsika P300 amplitude poyerekeza ndi odzipereka athanzi [57] . Zomwe zapezekazi zikusonyeza kuti mavuto okhudzana ndi kugwiritsa ntchito mankhwala osokoneza bongo amatha kudziwika ndi kusagawa bwino zinthu zomwe zimafunika kuti munthu azitha kuyang'ana kwambiri zinthu zomwe zimamukhudza (zosakhudzana ndi mankhwala osokoneza bongo) komanso kukonda kwambiri zinthu zomwe zimamukhudza. Kuchepa kwa P300 amplitude kungakhalenso chizindikiro cha matenda a endophenotypic. Kafukufuku wa zochitika zokhudzana ndi zochitika zomwe zimayang'ana kwambiri kufunika kwa cocaine ndi heroin cues akuwonetsanso zolakwika m'magawo omaliza a ERP (>300 milliseconds; late positive potential, LPP) m'madera akutsogolo, zomwe zingasonyezenso chilakolako ndi kugawa chidwi [58] - [60] . LPP imakhulupirira kuti ikuwonetsa kugwidwa koyambirira kwa chidwi (400 mpaka 1000 msec) komanso pambuyo pake kupitilira kwa zinthu zomwe zimamulimbikitsa. Anthu omwe ali ndi vuto la kugwiritsa ntchito cocaine anali atakweza miyezo yoyambirira ya LPP poyerekeza ndi odzipereka athanzi omwe akusonyeza kuti ndi gawo lothandizira kuti munthu azitha kuyang'ana kwambiri chidwi komanso mayankho ochepetsedwa kuzinthu zosangalatsa zamaganizo. Komabe, miyezo yomaliza ya LPP sinali yosiyana kwambiri ndi yomwe ili mwa odzipereka athanzi [61] . Zomwe zimayambitsa kuthekera kwa P300 kokhudzana ndi zochitika zokhudzana ndi zolinga zimakhulupirira kuti ndi parietal cortex ndi cingulate [62] . Chifukwa chake, zochita zonse za dACC mu kafukufuku wa CSB wapano ndi zochita za P300 zomwe zanenedwa mu kafukufuku wakale wa CSB zitha kuwonetsa njira zofanana zogwirira chidwi. Mofananamo, maphunziro onsewa akuwonetsa mgwirizano pakati pa miyeso iyi ndi chilakolako chowonjezeka. Apa tikuwonetsa kuti zochita za dACC zimagwirizana ndi chilakolako, chomwe chingawonetse chizindikiro cha chilakolako, koma sichikugwirizana ndi kukonda chitsanzo cha chilimbikitso cha zizolowezi.